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Menstruation-related angioedema treated with tranexamic acid
1Department of Gynecology and Obstetrics, University Hospital, Linköping, Sweden.
Acta Obstetricia Et Gynecologica Scandinavica
|January 1, 1988
Summary
Menstruation-related angioedema, causing cyclical hoarseness, resolved with contraceptive pills and pregnancy. Tranexamic acid proved effective, suggesting its use for secondary and idiopathic angioedema.
Area of Science:
- Otolaryngology
- Gynecology
- Allergy and Immunology
Background:
- Angioedema is a potentially serious condition characterized by swelling, often affecting the larynx.
- Menstruation-related angioedema is a rare subtype, presenting unique diagnostic and therapeutic challenges.
Observation:
- A case study details a patient experiencing cyclical hoarseness due to laryngeal edema, specifically linked to menstrual cycles.
- Symptoms resolved during oral contraceptive use and pregnancy, recurring post-partum with menstruation onset.
Findings:
- A successful therapeutic trial utilizing tranexamic acid was documented for managing menstruation-related angioedema.
- This suggests tranexamic acid's potential efficacy in treating similar cases.
Implications:
- The findings suggest tranexamic acid should be considered as a treatment option for secondary and idiopathic angioedema.
- Further research into hormonal influences on angioedema and tranexamic acid's role is warranted.