Related Experiment Video
Updated: Jan 29, 2026

Endotracheal Intubation of Rabbits Using a Polypropylene Guide Catheter
Published on: November 13, 2017
Uncuffed Endotracheal Tubes: Not Appropriate for Pediatric Critical Care Transport
Thomas E Pearson1, Meg A Frizzola2, Henry H Khine3
1Department of Nursing, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE.
Insights
Using uncuffed endotracheal tubes in critically ill children during transport often leads to complications. Many require urgent replacement with cuffed tubes after arrival at a pediatric intensive care unit.
Area of Science:
- Pediatric Critical Care Medicine
- Transport Medicine
- Airway Management
Background:
- The use of uncuffed endotracheal tubes in pediatric critical care transport lacks assessment.
- Complications may necessitate tube replacement upon arrival at a tertiary facility.
Purpose of the Study:
- To evaluate the incidence of complications associated with uncuffed endotracheal tubes in interfacility pediatric critical care transport.
- To determine the need for urgent reintubation after transport.
Main Methods:
- Retrospective case review of intubated pediatric patients transported over three years.
- Analysis of urgent reintubation rates for uncuffed versus cuffed endotracheal tubes.
Main Results:
- 55 of 213 intubated patients (25.8%) used uncuffed endotracheal tubes.
- 24 patients (43.6% of uncuffed group) required urgent tube replacement due to ventilation issues.
- No cuffed endotracheal tubes required replacement.
Conclusions:
- Uncuffed endotracheal tubes in critically ill children undergoing interfacility transport lead to a significant rate of urgent replacement.
- Repeat laryngoscopy and associated risks are common when uncuffed tubes are used prior to tertiary pediatric care.
Objective:
The effect of using uncuffed endotracheal tubes in children during interfacility critical care transport has not yet been assessed. We hypothesized that many children with uncuffed endotracheal tubes experience complications leading to replacement with a cuffed tube after arrival at a tertiary pediatric care facility.
Methods:
We conducted a retrospective case review of all intubated patients transported by our dedicated pediatric critical care transport team to our pediatric intensive care unit over a 3-year period. The incidence of urgent reintubation was studied.
Results:
A total of 213 children were referred for transport with an endotracheal tube in place, with 55 of those with an uncuffed endotracheal tube (25.8% of all intubated patients). Of those with uncuffed tubes, 24 patients needed their tubes replaced on an urgent basis by the medical team because of issues with ineffective ventilation (43.6% of patients with uncuffed tubes or 11.3% of all intubated patients). No cuffed tubes required replacement.
Conclusion:
Placing an uncuffed endotracheal tube in the critically ill child who is referred to tertiary pediatric care results in a significant number of these patients undergoing a repeat laryngoscopy, with all associated risks, to replace the uncuffed tube with a cuffed tube.
Related Concept Videos
Endotracheal Tube Extubation
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
Endotracheal Intubation II: Nursing Management
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
Critical Region, Critical Values and Significance Level
In hypothesis testing, a sample statistic is converted to a test statistic using z, t, or chi-square distribution. A critical region is an area under the curve in probability distributions demarcated by the critical value. When the test statistic falls in this region, it suggests that the null hypothesis must be rejected. As this region contains all those values of the...
Critical Values
Endotracheal Intubation I: Procedure
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
Facilitated Transport

