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Updated: Jan 29, 2026
Quantitative Metabolomics of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry
Published on: January 5, 2021
Comprehensive structural characterization of phenolics in litchi pulp using tandem mass spectral molecular networking
Qiang Lyu1, Ting-Hao Kuo2, Chongde Sun3
1Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China; Department of Chemistry, National Taiwan University, Taipei 10617, Taiwan.
Abstract:
Phenolic compounds are a large class of plant secondary metabolites with various health-promoting effects, and are known for their structural diversity. Therefore, high efficiency characterization of phenolic profiles is of key importance in identifying their potential bioactivity. In the present study, Global Natural Products Social (GNPS) Molecular Networking was applied to trace the phenolic compounds in plants, which allowed the characterization of 9 procyanidins and 11 flavonoid glycosides (di-, tri-, or tetra-saccharides of kaempferol, quercetin, isorhamnetin and myricetin) in litchi pulp extracts. Six compounds were reported for the first time in litchi pulp. In addition, quercetin-3-O-rutinoside-(1 → 2)-O-rhamnoside, the most abundant flavonoid glycoside in litchi pulp, was proved to have considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts.
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