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Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
05:32

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Published on: August 11, 2023

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Stroke Risk Before and After Central Retinal Artery Occlusion in a US Cohort

Kevin D Chodnicki1, Jose S Pulido1, David O Hodge2

  • 1Department of Ophthalmology, Mayo Clinic, Rochester, MN.

Mayo Clinic Proceedings
|February 4, 2019
PubMed

Insights

Central retinal artery occlusion (CRAO) is often accompanied by stroke, transient ischemic attack (TIA), or amaurosis fugax. These events necessitate prompt embolic work-ups for patients experiencing CRAO.

Area of Science:

  • Ophthalmology
  • Neurology
  • Vascular Medicine

Background:

  • Central retinal artery occlusion (CRAO) is a critical condition affecting vision.
  • Understanding the associated risks of cerebrovascular events is crucial for patient management.

Purpose of the Study:

  • To determine the incidence of ischemic stroke, transient ischemic attack (TIA), and amaurosis fugax in proximity to CRAO.
  • To assess the timing of these events relative to CRAO.

Main Methods:

  • Retrospective review of 300 patients diagnosed with CRAO between 2001 and 2016.
  • Analysis of ischemic stroke, TIA, and amaurosis fugax events occurring within 15 days before and after CRAO.
  • Comparison of stroke risk based on the etiology of CRAO (embolic vs. unknown).

Main Results:

  • 16.0% of patients experienced symptomatic ischemic stroke around the time of CRAO.
  • TIA and amaurosis fugax were observed in 1.7% and 8.7% of patients, respectively.
  • Patients with embolic CRAO had a higher risk of stroke (7%) compared to those with unknown causes (1.3%).

Conclusions:

  • Symptomatic stroke, TIA, and amaurosis fugax are common occurrences associated with CRAO.
  • Central retinal artery occlusion warrants urgent evaluation for embolic sources.
  • Timely diagnosis and management of CRAO can mitigate risks of associated vascular events.
Abstract

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