Related Experiment Video
Updated: Jan 29, 2026

Rapid and Low-cost Prototyping of Medical Devices Using 3D Printed Molds for Liquid Injection Molding
Published on: June 27, 2014
CAD-CAM milled versus rapidly prototyped (3D-printed) complete dentures: An in vitro evaluation of trueness
Nicole Kalberer1, Albert Mehl2, Martin Schimmel3
1Research and Teaching Assistant, Division of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland.
Statement Of Problem:
Complete dentures fabricated by computer-aided design and computer-aided manufacturing (CAD-CAM) techniques have become popular. The 2 principal CAD-CAM techniques, milling and rapid prototyping (3D printing), used in the fabrication of complete dentures have been reported to yield clinically acceptable results. However, clinical trials or in vitro studies that evaluated the accuracy of the 2 manufacturing techniques are lacking.
Purpose:
The purpose of this in vitro study was to compare the differences in trueness between the CAD-CAM milled and 3D-printed complete dentures.
Material And Methods:
Two groups of identical maxillary complete dentures were fabricated. A 3D-printed denture group (3DPD) (n=10) and a milled denture group (MDG) (n=10) from a reference maxillary edentulous model. The intaglio surfaces of the fabricated complete dentures were scanned at baseline using a laboratory scanner. The complete dentures were then immersed in an artificial saliva solution for a period of 21 days, followed by a second scan (after immersion in saliva). A third scan (after the wet-dry cycle) was then made after 21 days, during which the complete dentures were maintained in the artificial saliva solution during the day and stored dry at night. A purpose-built 3D comparison software program was used to analyze the differences in the trueness of the complete dentures. The analyses were performed for the entire intaglio surface and specific regions of interest: posterior crest, palatal vault, posterior palatal seal area, tuberosity, anterior ridge, vestibular flange, and mid-palatal raphae. Independent t tests, ANOVA, and post hoc tests were used for statistical analyses (α=.05).
Results:
The trueness of the milled prostheses was significantly better than that of the rapid prototyping group with regard to the entire intaglio surface (P<.001), posterior crest (P<.001), palatal vault (P<.001), posterior palatal seal area (P<.001), tuberosity (P<.001), anterior ridge (baseline: P<.001; after immersion in saliva: P=.001; after the wet-dry cycle: P=.011), vestibular flange (P<.001), and mid-palatal raphae (P<.001).
Conclusions:
The CAD-CAM, milled complete dentures, under the present manufacturing standards, were superior to the rapidly prototyped complete dentures in terms of trueness of the intaglio surfaces. However, further research is needed on the biomechanical, clinical, and patient-centered outcome measures to determine the true superiority of one technique over the other with regard to fabricating complete dentures by CAD-CAM techniques.
More Related Videos
Related Concept Videos
C4 Pathway and CAM
C4 Pathway
The C4 pathway is used by plants such as...
Concepts and Prototypes
The brain organizes this information using concepts, which are mental categories grouping linguistic data,...
Rapidly Varying Flow
Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs
Self-Evaluation: Self-Enhancement and Self-Verification
RACE - Rapid Amplification of cDNA Ends

