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[Brown's syndrome].

D Denis1, P Lebranchu2, M Beylerian1

  • 1Service d'ophtalmologie, CHU Secteur Nord Marseille, chemin des Bourrély, 13015 Marseille, France.

Journal Francais D'Ophtalmologie
|February 4, 2019
PubMed
Summary
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Brown's syndrome involves superior oblique muscle abnormalities, causing limited eye movement. Diagnosis relies on imaging, with treatment rarely needing surgery.

Area of Science:

  • Ophthalmology
  • Neurology
  • Medical Imaging

Background:

  • Brown's syndrome is an oculomotor disorder stemming from superior oblique muscle abnormalities.
  • It presents as limited elevation in adduction, affecting the inferior oblique muscle's action field.
  • Causes can be congenital or acquired (inflammatory, infectious, traumatic, iatrogenic).

Purpose of the Study:

  • To review the diagnostic and management strategies for Brown's syndrome.
  • To highlight the role of advanced imaging in diagnosis.
  • To discuss treatment indications and outcomes.

Main Methods:

  • Review of clinical and paraclinical signs suggestive of Brown's syndrome.
  • Emphasis on the diagnostic utility of cerebral and orbital imaging (CT, MRI).
Keywords:
AcquiredAcquisAnomalous head positionBrown's syndromeCerebral and orbital imagingCongenitalCongénitalImagerie cérébro-orbitaireLimitation of elevation in adductionLimitation élévation adductionSyndrome de Brown

Related Experiment Videos

  • Analysis of spontaneous, etiological, and surgical treatment approaches.

    • Main Results:

    • Clinical and imaging findings are crucial for diagnosing both congenital and acquired Brown's syndrome.
    • Improvement can occur spontaneously or with etiological treatment.
    • Surgical intervention is reserved for specific cases with torticollis, hypotropia, strabismus, or impaired binocular vision.

    Conclusions:

    • Accurate diagnosis of Brown's syndrome requires a combination of clinical evaluation and advanced imaging.
    • While conservative management and etiological treatment can lead to improvement, surgery is indicated for severe functional deficits.
    • Long-term surgical outcomes for Brown's syndrome remain variable.