The moment of intraventricular hemorrhage

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Updated: Oct 31, 2026

Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model
08:18

Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model

Published on: February 8, 2022

M Funato1, H Tamai, R Kodaka

  • 1Department of Pediatrics, Yodogawa Christian Hospital, Osaka, Japan.

Brain & Development
|January 1, 1988
PubMed

Insights

Continuous ultrasound monitoring can detect the precise moment of intraventricular hemorrhage (IVH) in premature infants. This method identified IVH in one infant without concurrent vital sign changes or interventions.

Area of Science:

  • Neonatal Medicine
  • Medical Imaging
  • Pediatric Neurology

Background:

  • Intraventricular hemorrhage (IVH) is a significant complication in premature infants.
  • Early detection of IVH is crucial for timely intervention and improved outcomes.
  • Current monitoring methods may not pinpoint the exact timing of IVH onset.

Purpose of the Study:

  • To evaluate the efficacy of continuous linear scanning ultrasound for real-time detection of intraventricular hemorrhage (IVH) in high-risk neonates.
  • To determine if IVH occurs during periods of physiological stability or in response to specific events.

Main Methods:

  • Continuous 48-hour monitoring of the germinal layer using linear scanning ultrasound in 7 neonates weighing under 1,000 g.
  • Utilized VHS videotape for recording and subsequent analysis of ultrasound data.
  • Correlated ultrasound findings with infant's heart rate, systemic blood pressure, and concurrent medical interventions.

Main Results:

  • Four out of seven infants developed intraventricular hemorrhage (IVH).
  • The precise moment of IVH onset was successfully captured via ultrasound in one 755 g infant (24 weeks gestational age).
  • IVH occurred without significant changes in heart rate or blood pressure, and independently of direct medical manipulations like endotracheal suctioning or heel punctures.

Conclusions:

  • Continuous ultrasound monitoring is a feasible method for identifying the exact timing of intraventricular hemorrhage (IVH) in extremely low birth weight infants.
  • Intraventricular hemorrhage can manifest during periods of apparent hemodynamic stability.
  • Further research is warranted to explore the clinical implications of IVH timing detected by continuous ultrasound.

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