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Hypoglycaemic coma associated with anorexia nervosa.

J Smith1

  • 1Department of Psychiatry, Royal Adelaide Hospital, South Australia.

The Australian and New Zealand Journal of Psychiatry
|December 1, 1988
PubMed
Summary
This summary is machine-generated.

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Profound hypoglycemia is a rare complication of anorexia nervosa. Key risk factors include low body weight, fasting, and infection, but prompt treatment can lead to recovery.

Area of Science:

  • Endocrinology
  • Metabolic Disorders
  • Nutritional Psychiatry

Background:

  • Anorexia nervosa is an eating disorder characterized by self-starvation and a profound fear of gaining weight.
  • Hypoglycemia, or low blood sugar, is a serious complication that can occur in individuals with anorexia nervosa.

Observation:

  • This report details an additional case of profound hypoglycemia in a patient with anorexia nervosa.
  • A review of existing literature identified seven previous cases of this complication.

Findings:

  • Major risk factors for hypoglycemia in anorexia nervosa include body weight below 30 kg, periods of fasting, and concurrent infections.
  • Excessive exercise may also contribute to the development of hypoglycemia.
  • Proposed pathogenic mechanisms involve depleted liver glycogen, impaired gluconeogenesis, and defective glucagon secretion.

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Implications:

  • Hypoglycemic coma associated with anorexia nervosa carries a high mortality rate.
  • However, prompt medical intervention can lead to complete recovery, as demonstrated in the reported case.