Related Experiment Video
Updated: Jan 29, 2026
10:37
Development of Recombinant Proteins to Treat Chronic Pain
Published on: April 11, 2018
10.0K
Novel Approaches for Treating Pain in Children
William Splinter1,2,3
1Palliative Medicine, Children's Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, Ontario, K1H 8L1, Canada. splinter@cheo.on.ca.
Current Oncology Reports
|February 5, 2019
Summary
Innovative pain management for children, particularly those in palliative care, includes new uses for existing drugs like ketamine and novel medications such as cannabinoids. Novel administration methods like intranasal and inhalation are also explored for pediatric pain relief.
Area of Science:
- Pediatric Palliative Medicine
- Pain Management
- Pharmacology
Background:
- Effective pain management is essential in pediatric palliative care.
- Novel approaches to pain control are increasingly important for children with complex needs.
Purpose of the Study:
- To review innovative strategies for managing pain in children.
- To explore new pharmaceutical options and drug delivery methods in pediatric pain management.
Main Methods:
- Literature review of recent advancements in pediatric pain management.
- Focus on novel medications (e.g., cannabinoids) and innovative administration techniques (e.g., intranasal, inhalation).
Main Results:
- Current strategies integrate new uses of old drugs (ketamine, lidocaine) and new medications (cannabinoids).
- Innovative administration technologies like atomizers and intranasal delivery are being utilized.
- These novel approaches, though not always originating in pediatrics, offer new ways to manage pediatric pain.
Conclusions:
- The review highlights the evolving landscape of pediatric pain management.
- Combining established and novel pharmacological agents with creative delivery systems enhances palliative care for children.
- Further research into these innovative methods is warranted to optimize pain relief in pediatric populations.
Related Concept Videos
01:20Pain
1.4K
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.4K
01:29Drug Dosing: Infants and Children
292
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
292
01:25Analgesia and Pain Management
1.6K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.6K
01:20Frustration and Conflict: Approach-Approach, Approach-Avoidance
528
Frustration occurs when people are obstructed or prevented from achieving a desired goal or fulfilling a perceived need. For example, when someone's input is ignored in a discussion, it can lead to feelings of frustration. Conflict, however, arises from opposing interests, goals, or actions. Conflicts can take various forms based on the nature of these opposing desires or goals.
One common type of conflict is the Approach–Approach Conflict. In this case, a person faces two desirable...
One common type of conflict is the Approach–Approach Conflict. In this case, a person faces two desirable...
528
01:24Primary Motives: Sleep, Sex, and Pain Avoidance
5.6K
Primary motives such as sleep, sex, and pain avoidance are crucial drivers of behavior in humans and animals. These motives ensure survival, reproductive success, and overall well-being by prompting actions that meet essential bodily needs.
Sleep is a fundamental physiological drive that fosters a state of restfulness crucial for several bodily functions. It facilitates body restoration, the process by which the body repairs, rejuvenates, and maintains itself during sleep, including memory...
Sleep is a fundamental physiological drive that fosters a state of restfulness crucial for several bodily functions. It facilitates body restoration, the process by which the body repairs, rejuvenates, and maintains itself during sleep, including memory...
5.6K
01:20Actuarial Approach
306
The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
306