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The human ear cannot distinguish between two sources of sound if they happen to reach within a specific time interval, typically 0.1 seconds apart. More than this, and they are perceived as separate sources.
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Updated: Jan 29, 2026

Author Spotlight: Optimized Lung MRI Protocol with Computationally Efficient Reconstruction Methods
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Author Spotlight: Optimized Lung MRI Protocol with Computationally Efficient Reconstruction Methods

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Echo planar time-resolved imaging (EPTI).

Fuyixue Wang1,2, Zijing Dong1,3, Timothy G Reese1

  • 1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts.

Magnetic Resonance in Medicine
|February 5, 2019
PubMed
Summary
This summary is machine-generated.

A new echo planar time-resolved imaging (EPTI) technique rapidly acquires distortion- and blurring-free images for advanced multi-contrast and quantitative imaging. This method enables faster, more accurate MRI scans with improved image quality.

Keywords:
EPIdistortion-freefMRImulti-contrastquantitative imaging

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Area of Science:

  • Magnetic Resonance Imaging
  • Biomedical Engineering

Background:

  • Echo planar imaging (EPI) is widely used but suffers from geometric distortions and blurring.
  • These artifacts limit the quality and accuracy of EPI-based imaging sequences.

Purpose of the Study:

  • To develop an efficient, distortion- and blurring-free multi-shot EPI technique.
  • The goal is to enable time-resolved multiple-contrast and quantitative imaging.

Main Methods:

  • Introduced echo planar time-resolved imaging (EPTI), a novel multi-shot EPI technique.
  • Utilized ky-t space encoding with accelerated spatio-temporal CAIPI sampling.
  • Employed B0-informed parallel imaging reconstruction and simultaneous multi-slice acquisition.
  • Developed a method for self-estimation and correction of shot-to-shot B0 variations.

Main Results:

  • EPTI demonstrated the ability to produce distortion- and blurring-free images at multiple echo times (TEs).
  • Evaluated under simulated acceleration, B0-inhomogeneity, and shot-to-shot B0 variations.
  • In vivo demonstrations at 3T included quantitative mapping (T2, T2*, PD, susceptibility) in 28s and multi-echo quantitative T2* fMRI with 3.3s temporal resolution.

Conclusions:

  • EPTI is a novel approach for multi-contrast and quantitative imaging.
  • It enables fast acquisition of distortion- and blurring-free images at multiple TEs.
  • This technique significantly advances MRI capabilities for various applications.