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Published on: October 1, 2007
[Intranodal lymphangiography in pediatric chylothorax, a diagnostic and therapeutic tool]
J Jiménez Gómez1, M Gómez Cervantes1, V Núñez Cerezo1
1Departamento de Cirugía Pediátrica. Hospital Universitario La Paz. Madrid.
Insights
Intranodal lymphangiography (IL) with ethiodized oil shows promise in managing pediatric chylothorax, potentially sealing lymphatic leaks in postsurgical cases. This technique offers a diagnostic and therapeutic option when other treatments fail or are not feasible.
Area of Science:
- Pediatric Interventional Radiology
- Thoracic Surgery
- Lymphatic Imaging
Background:
- Secondary chylothorax in children carries high morbidity.
- Thoracic duct embolization (TDE) after intranodal lymphangiography (IL) is established in adults but lacks pediatric data.
- This study evaluates the experience with IL and TDE in pediatric refractory chylothorax.
Observation:
- Four pediatric patients with refractory chylothorax were treated.
- Three cases were secondary to cardiothoracic surgery; one was due to venous thrombosis.
- Medical management failed to reduce thoracic output prior to IL.
Findings:
- Successful thoracic duct catheterization was achieved in one patient, but embolization was not possible.
- Chylothorax resolved in all three postsurgical patients, irrespective of lymphatic visualization.
- Ethiodized oil may contribute to sealing lymphatic leaks in postsurgical chylothorax.
Implications:
- Intranodal lymphangiography (IL) serves as a valuable diagnostic and therapeutic tool in pediatric chylothorax.
- Ethiodized oil embolization could be a viable treatment for postsurgical lymphatic leaks.
- IL presents an alternative for critically ill children or those unsuitable for TDE.
Introduction:
High morbidity has been described in secondary chylothorax. Thoracic duct embolization (TDE) after intranodal lymphangiography (IL) is one of the treatments in adults but there is poor experience in children. We aim to describe our experience with this technique for refractory pediatric chylothorax.
Methods:
A retrospective study of patients with refractory chylothorax treated with thoracic duct embolization at our Institution in the last 4 years was performed. Lymphatic vessels visualization was obtained by intranodal lymphangiography with ethiodized oil. Demographic and clinical data as well as imaging findings were collected.
Results:
A total of 4 patients were treated during the study period with a median of age and weight of 2.5 months (1-16) and 4.25 kg (2.8-10) respectively. Chylothorax was secondary to cardiothoracic surgery in 3 patients and to venous thrombosis in the other one. Medical treatment was provided during a median of 47 days (13-56) without benefit in thoracic output [median: 46 ml/kg/day (19-64)]. After IL, thoracic duct catheterization was achieved in one patient however embolization was not possible. Chylothorax stopped in the 3 post-surgical patients regardless of how much lymphatic visualization was achieved in IL. In the venous thrombosis patient surgical treatment was performed 6 days after the study.
Conclusion:
IL can be a diagnostic and therapeutic tool in children. Ethiodized oil seems to seal lymphatic leak in postsurgical chylothorax. IL could be an option for chylothorax in patients too sick for surgical treatment or in whom thoracic duct embolization is not feasible.
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