Survival and reinterventions after isolated proximal aortic repair in acute type A aortic dissection

Conventional treatment for acute type A dissection is the replacement of the ascending aorta. This study demonstrates the results of a conventional approach with isolated proximal repair combined with concomitant endovascular procedures.

Replacement of the ascending aorta with or without an open distal anastomosis was defined as isolated proximal repair and was performed in 562/588 patients between January 2004 and June 2017. A total of 68% were DeBakey type I and 32% were DeBakey type II aortic dissections. Concomitant procedures were thoracic endovascular aortic repair (3.6%); visceral, renal and iliac stents (2%); and peripheral bypasses (1.1%). Mean follow-up was 4.6 ± 3.5 years with a 98% follow-up rate. Early and long-term survival, reintervention rates and risk factors were analysed.

Overall, the in-hospital mortality rate was 10.7%, 5.6% in DeBakey type II and 13% in DeBakey type I aortic dissection (P = 0.008). Risk factors for in-hospital mortality were age [odds ratio (OR) 1.03], chronic obstructive lung disease (OR 3.98), coronary artery disease (OR 2.19), Penn class BC (OR 15.41) and cardiopulmonary bypass time (OR 1.01). The 5- and 10-year survival rates, including in-hospital mortality, were 71% and 54% for type I and 73% and 65% for type II aortic dissection, respectively (P = 0.14). Freedom from reintervention after 5 and 10 years was 96% and 94% for DeBakey type II aortic dissection and 86% and 78% for type I (P < 0.001).

Combined with concomitant endovascular procedures, good short- and long-term results can be achieved in DeBakey type I and II aortic dissection. The reintervention rate is higher in DeBakey type I but can be managed open and endovascularly with good results.