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Updated: Jan 29, 2026

Kupffer Cell Isolation for Nanoparticle Toxicity Testing
Published on: August 18, 2015
Toxic effects of magnetic nanoparticles on normal cells and organs
Ziyu Jiang1, Kuizhong Shan2, Jie Song3
1Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People's Republic of China; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, People's Republic of China.
Abstract:
Magnetic nanoparticles (MNPs) are promising candidates for drug delivery and treatment of various disorders. Toxicity evaluation is a critical point in the development of nanoformulations and therefore, draws considerable attention. Formulations involving individual or combinatorial nanoparticle suspensions might be used for targeted delivery and treatment. This might be a evaluated further for safety related issues considering future medications based on MNPs. Nanoparticle distribution in the body is dependent on its surface characteristics. Size, dose and routes of nanoparticle entry have to be taken into consideration for future assays.
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