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Cough in pulmonary tuberculosis: Existing knowledge and general insights
1Department of Respiratory Medicine, Imperial College Healthcare NHS Trust, London, UK.
Pulmonary Pharmacology & Therapeutics
|February 5, 2019
Summary
Coughing plays a key role in transmitting tuberculosis (TB), caused by Mycobacterium tuberculosis. This review explores how TB cough impacts infectiousness, its causes, and treatments.
Area of Science:
- Pulmonary Medicine
- Infectious Diseases
- Microbiology
Background:
- Tuberculosis (TB) is a major global infectious disease.
- Cough is a primary symptom of pulmonary TB and a likely transmission route for Mycobacterium tuberculosis.
- Research on the role of cough in TB transmission is limited.
Purpose of the Study:
- To review current evidence on the infectiousness of cough in TB.
- To discuss clinical correlates, causes, and unique characteristics of TB-related cough.
- To explore treatment and subjective awareness of cough in TB patients.
Main Methods:
- Literature review of existing evidence on TB and cough.
- Synthesis of information on cough mechanisms, transmission, and clinical aspects.
- Discussion of potential unique features of cough in TB.
Main Results:
- Cough is a significant factor in Mycobacterium tuberculosis transmission.
- Understanding of cough mechanisms and infectiousness in TB is evolving.
- Evidence links cough characteristics to disease progression and transmission potential.
Conclusions:
- Further research is needed to fully understand the role of cough in TB.
- Targeting cough may be a strategy to reduce TB transmission.
- Addressing cough symptoms is crucial for patient management and public health.
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