Carotid-vertebral artery bypass with saphenous vein graft for symptomatic vertebrobasilar insufficiency
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Updated: Jan 29, 2026

Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg
Published on: November 19, 2019
Hongzhou Duan1, Dapeng Mo1,2, Yang Zhang1
11Department of Neurosurgery, Peking University First Hospital; and.
Insights
External carotid artery-saphenous vein-vertebral artery bypass effectively treats symptomatic vertebral or subclavian artery steno-occlusion, preventing recurrent ischemic events in the vertebrobasilar territory.
Area of Science:
- Vascular Surgery
- Neurology
- Interventional Cardiology
Background:
- Proximal vertebral artery (VA) or subclavian artery (ScA) steno-occlusion presents a poor prognosis and high stroke recurrence risk.
- Medical therapies, including antiplatelet or anticoagulant drugs, are often insufficient for these patients.
Observation:
- This study retrospectively analyzed 7 patients with symptomatic proximal VA or ScA steno-occlusion.
- Patients presented with V1 segment occlusion, V1 in-stent restenosis, or proximal ScA occlusion.
- The V2 segment of the cervical VA was patent and perfused via collateral vessels in these cases.
Findings:
- All 7 patients underwent successful external carotid artery (ECA)-saphenous vein (SV)-VA bypass surgery.
- Postoperative angiography confirmed patent anastomoses in all cases.
- Patients experienced symptom improvement with no new neurological deficits during 12-78 months of follow-up.
Implications:
- ECA-SV-VA bypass is a viable treatment option for medically refractory vertebrobasilar ischemic events due to proximal VA or ScA disease.
- This surgical approach offers a solution when the V2 cervical VA segment remains patent.
- The procedure demonstrates long-term efficacy in preventing further ischemic events.
Abstract:
OBJECTIVESymptomatic steno-occlusion of the proximal vertebral artery (VA) or subclavian artery (ScA) heralds a poor prognosis and high risk of stroke recurrence despite medical therapy, including antiplatelet or anticoagulant drugs. In some cases, the V2 segment of the cervical VA is patent and perfused via collateral vessels. The authors describe 7 patients who were successfully treated by external carotid artery (ECA)-saphenous vein (SV)-VA bypass.METHODSSeven cases involving symptomatic patients were retrospectively studied: 3 cases of V1 segment occlusion, 2 cases of severe in-stent restenosis in the V1 segment, and 2 cases of occlusion of the proximal ScA. All patients underwent ECA-SV-VA bypass. The ECA was isolated and retracted, and the anterior wall of the transverse foramen was unroofed. The VA was exposed, and then the 2 ends of the SV were anastomosed to the VA and ECA in an end-to-side fashion.RESULTSSurgical procedures were all performed as planned, with no intraoperative complications. There were 2 postoperative complications (severe laryngeal edema in one case and shoulder weakness in another), but both patients recovered fully and measures were taken to minimize laryngeal edema and its effects in subsequent cases. All patients experienced improvement of their symptoms. No new neurological deficits were reported. Postoperative angiography demonstrated that the anastomoses were all patent, and analysis of follow-up data (range of follow-up 12-78 months) revealed no further ischemic events in the vertebrobasilar territory.CONCLUSIONSThe ECA-SV-VA bypass is a useful treatment for patients who suffer medically refractory ischemic events in the vertebrobasilar territory when the proximal part of the VA or ScA is severely stenosed or occluded but the V2 segment of the cervical VA is patent.
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