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Adverse Hair Reactions to New Targeted Therapies for Cancer
J F Mir-Bonafé1, D Saceda-Corralo2, S Vañó-Galván2
1Servicio de Dermatología, Hospital de la Santa Creu i Sant Pau, Barcelona, España.
Actas Dermo-Sifiliograficas
|February 6, 2019
Summary
Targeted cancer therapies can cause unique hair changes. This review details adverse hair effects from these innovative immune-targeting drugs, aiding clinical understanding.
Area of Science:
- Oncology
- Dermatology
- Pharmacology
Background:
- Immune targeted therapies have revolutionized cancer treatment.
- These therapies can cause novel dermatologic side effects, including hair changes.
- Existing literature lacks a comprehensive overview of these adverse hair effects.
Purpose of the Study:
- To systematically review and characterize adverse hair effects associated with targeted cancer therapies.
- To consolidate information on hair-related side effects from various targeted drugs.
- To provide a reference for clinicians managing these side effects.
Main Methods:
- Exhaustive literature search was performed.
- Studies reporting hair changes in patients receiving targeted therapies were included.
- Data on hair growth, color, and shape alterations were extracted.
Main Results:
- Targeted therapies can induce significant alterations in hair growth, including alopecia and hypertrichosis.
- Changes in hair color (e.g., graying) and texture (e.g., wiry or curly hair) are commonly observed.
- The specific hair effects vary depending on the targeted therapy used.
Conclusions:
- Adverse hair effects are a notable consequence of immune targeted cancer therapies.
- Understanding these effects is crucial for patient counseling and management.
- Further research is needed to elucidate the mechanisms and develop interventions for these side effects.
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