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Updated: Jan 29, 2026

Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
Recent Progress on Gold-Nanocluster-Based Fluorescent Probe for Environmental Analysis and Biological Sensing
Mingxian Liu1, Fenglin Tang1, Zhengli Yang1
1College of Chemistry and Chemical Engineering, Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, China West Normal University, Nanchong 637000, China.
Gold nanoclusters (AuNCs) offer stable, tunable fluorescence, making them superior fluorescent probes. This review covers AuNC synthesis and applications in environmental analysis and biological sensing.
Area of Science:
- Nanotechnology
- Materials Science
- Analytical Chemistry
Background:
- Gold nanoclusters (AuNCs) are emerging as key fluorescent probes.
- They exhibit superior fluorescence stability and tunable wavelengths compared to traditional organic dyes.
- This makes them highly attractive for various sensing applications.
Purpose of the Study:
- To review synthesis strategies for gold nanocluster-based fluorescent probes.
- To summarize their applications in environmental analysis and biological sensing.
- To highlight the advantages of AuNCs in fluorescence-based detection.
Main Methods:
- Exploration of diverse synthesis methodologies for AuNCs.
- Compilation of studies utilizing AuNCs for environmental pollutant detection.
- Review of research employing AuNCs for biological labeling, imaging, and sensing.
Main Results:
- Gold nanoclusters demonstrate significant potential as fluorescent probes.
- Their synthesis is adaptable, leading to probes with desirable optical properties.
- AuNCs show promise in detecting heavy metals and pollutants, and in biological applications.
Conclusions:
- Gold nanocluster-based fluorescent probes offer a robust platform for advanced sensing.
- Their tunable fluorescence and stability are advantageous over conventional probes.
- Continued research in AuNC synthesis and application will drive innovation in environmental and biological monitoring.
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