Related Experiment Video
Updated: Jan 29, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Catalyst-controlled cascade synthesis of bridged bicyclic tetrahydrobenz[b]azepine-4-ones
Michelle A Kroc1, Maciej Markiewicz, Wiktoria H Pace
1Department of Chemistry, University of Illinois at Chicago, 845 W. Taylor St. MC 111, Chicago, IL 60607, USA. lauralin@uic.edu.
Abstract:
A catalyst-controlled cascade reaction has been developed for the synthesis of bridged bicyclic tetrahydrobenz[b]azepin-4-ones from N-arylnitrones and allenes. This method expands the accessible structural diversity of a synthetically challenging heterocyclic scaffold and tunes a catalyst-sensitive process in a new direction.
Related Concept Videos
Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry
Intracellular Signaling Cascades
Rab Cascades
Design Example: Strain Gauge Bridge or Wheatstone Bridge
Wheatstone Bridge
Thus, for accurate resistance measurements, a...
Bridge rectifier
Operationally, the bridge rectifier allows current flow through two of its diodes during each...

