Related Experiment Video
Updated: Jul 26, 2026
Aplysia Ganglia Preparation for Electrophysiological and Molecular Analyses of Single Neurons
Published on: January 13, 2014
Abstract:
In 2017, The American Naturalist celebrated its 150th anniversary. It was founded as a journal of natural history, yet it developed into an important vehicle of the evolutionary synthesis. During the early years of the journal and through much of the twentieth century, evolutionary theory was developed to explain the history of nature before humankind existed to alter it-when time was expansive and uncommon events, though rare, were frequent enough to effect evolutionary change. Today, with the influence of human activity, dispersal patterns are fundamentally altered, genetic variation is locally limiting in small and fragmented populations, and environments are changing so rapidly that time itself seems limited. How can we use this theory, which was built to explain the past and which depends on an excess of chances and time, to address the challenges of the present and the future when chances are fewer and time seems so short? And does the habit of naturalists to observe, describe, and cultivate a fascination with nature have a place in contemporary science?
Related Concept Videos
02:14SN2 Reaction: Kinetics
In a chemical reaction, a relationship exists between the concentration of reactants and the rate at which the reaction proceeds. The study to measure this relationship is known as the kinetics of a chemical reaction. Kinetic studies are used to deduce the rate law of a chemical reaction, which provides information about the species involved during the transition state of the rate-determining step. Thus, kinetic studies help to derive the mechanism of a reaction.
02:27SN2 Reaction: Mechanism
The presence of the more electronegative halogen in the substrate creates a polarized carbon-halide bond. The halide pulls the electron cloud generating an electrophilic center at the carbon atom. Thus, the carbon atom carries a partial positive charge while the halide has a...
02:26SN2 Reaction: Transition State
When the nucleophile approaches the electrophilic carbon with its lone pairs, the halide acts as a leaving group and moves away with the electron-pair bonded to the carbon. Dotted partial bonds represent the bonds being formed or broken...
02:23SN2 Reaction: Stereochemistry
If the substrate is an achiral molecule at the α-carbon, the inversion of configuration is not observed.
02:25SN1 Reaction: Mechanism
Firstly, the haloalkane ionizes to generate a carbocation intermediate and a halide ion. This heterolytic cleavage is highly endothermic with large activation energy. The ionization of the substrate, facilitated by a polar...
02:15SN1 Reaction: Stereochemistry
In the first step of an SN1 reaction, the bond between the electrophilic carbon and the leaving group ionizes to generate the carbocation intermediate. The second step of the mechanism is the nucleophilic attack.
In the formed carbocation, the positively charged carbon is sp2 hybridized with a trigonal planar geometry. As all the three substituents lie on the same plane, a plane of symmetry for the...