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Gluten in Celiac Disease-More or Less?
Inna Spector Cohen1,2, Andrew S Day3, Ron Shaoul1,2
1Pediatric Gastroenterology & Nutrition Institute, Ruth Rappaport Children's Hospital, Rambam Medical Center, Haifa, Israel.
Rambam Maimonides Medical Journal
|February 6, 2019
Summary
Patients with celiac disease must strictly avoid gluten. Research suggests a daily gluten intake limit of 10-50 mg is safe, aligning with the definition of gluten-free products containing less than 20 parts per million gluten.
Area of Science:
- Gastroenterology
- Immunology
- Nutrition Science
Background:
- Celiac disease requires lifelong adherence to a strict gluten-free diet.
- Identifying safe gluten intake levels is crucial for patient management.
Purpose of the Study:
- To review the scientific literature on the upper limit of safe gluten content for celiac disease patients.
- To establish a recommended daily gluten intake threshold.
Main Methods:
- Systematic literature review of studies evaluating gluten tolerance in celiac disease.
- Analysis of established definitions for gluten-free food products.
Main Results:
- Recommended daily gluten intake for celiac patients should not exceed 10-50 mg.
- Gluten-free products are typically defined as containing less than 20 parts per million (ppm) of gluten.
Conclusions:
- A daily gluten intake of 10-50 mg is considered safe for individuals with celiac disease.
- Adherence to <20 ppm gluten in food products supports a safe gluten-free diet.
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