Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

32.3K
Overview
32.3K
Allergic Drug Reactions01:27

Allergic Drug Reactions

1.5K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.5K
Data Reporting and Recording01:24

Data Reporting and Recording

5.4K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K
Types of Reports I: Hands-off Report01:25

Types of Reports I: Hands-off Report

1.5K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K
Types of Reports II: Incident or Occurrence Report01:21

Types of Reports II: Incident or Occurrence Report

1.3K
An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.3K
Reaction Mechanisms03:06

Reaction Mechanisms

30.7K
Chemical reactions often occur in a stepwise fashion, involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs.
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
30.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Therapeutic Targeting of the Bradykinin B2 Receptor in Immunological and Vascular Diseases: Insights from Kinin Biology to Clinical Outcomes.

Clinical reviews in allergy & immunology·2026
Same author

Sebetralstat for on-demand treatment of hereditary angioedema: A pooled analysis of placebo-controlled clinical trials.

The World Allergy Organization journal·2026
Same author

Lonvoguran Ziclumeran - In Vivo CRISPR Gene Editing in Hereditary Angioedema.

The New England journal of medicine·2026
Same author

Shared Decision-Making and Health-Related Quality of Life in Drug Allergy.

The journal of allergy and clinical immunology. In practice·2026
Same author

The 2025 WAO Guidelines for the classification, diagnosis, and treatment of hereditary angioedema, with consideration of worldwide disparities.

The World Allergy Organization journal·2026
Same author

Lessons Learned: Approaches to Delabeling Penicillin Allergy-A Clinical Management Review of Population-Level Strategies.

The journal of allergy and clinical immunology. In practice·2026
Same journal

Impact of Nursing Leadership for Surgical Excellence Program on Perioperative Care and Patient Safety in Low-Income Countries: A Mixed-Methods Study.

Journal of patient safety·2026
Same journal

Strengthening Telemetry Safety Through Standardized Physiological Parameter Monitor Technician Education: A Practice-Based Framework.

Journal of patient safety·2026
Same journal

Implementing Shortened Fasting Protocols Before Cardiac Catheterization: A Quality Improvement Initiative.

Journal of patient safety·2026
Same journal

A Qualitative Study Exploring the Views and Experiences of UK Maternity Healthcare Professionals Towards Adverse Event Disclosure.

Journal of patient safety·2026
Same journal

Clinical and Safety Outcomes of Patients Admitted to Different Specialty Wards: The Prospective, Multi-center, Controlled SISIFO Study.

Journal of patient safety·2026
Same journal

Responsive Learning and Proactive Harm Prevention: Development of a Tiered Event Review Continuum.

Journal of patient safety·2026
See all related articles

Related Experiment Video

Updated: Jan 29, 2026

Zebrafish Animal Model for the Study of Allergic Reactions in Response to Tick Saliva Biomolecules
07:01

Zebrafish Animal Model for the Study of Allergic Reactions in Response to Tick Saliva Biomolecules

Published on: September 16, 2022

2.2K

Allergic Reactions Captured by Voluntary Reporting.

Kimberly G Blumenthal, Anna R Wolfson, Yu Li

  • 1Edward P. Lawrence Center for Quality and Safety, Massachusetts General Hospital and the Massachusetts General Professional Organization.

Journal of Patient Safety
|February 6, 2019
PubMed
Summary
This summary is machine-generated.

Hospital adverse reactions (ARs), including hypersensitivity reactions (HSRs), are common. Allergy safety efforts should focus on severe reactions to drugs like beta-lactams and vancomycin, as well as blood products and devices.

More Related Videos

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.8K
Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

47.4K

Related Experiment Videos

Last Updated: Jan 29, 2026

Zebrafish Animal Model for the Study of Allergic Reactions in Response to Tick Saliva Biomolecules
07:01

Zebrafish Animal Model for the Study of Allergic Reactions in Response to Tick Saliva Biomolecules

Published on: September 16, 2022

2.2K
The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.8K
Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

47.4K

Area of Science:

  • Healthcare safety research
  • Clinical immunology
  • Pharmacovigilance

Background:

  • Hospital adverse reactions (ARs), especially hypersensitivity reactions (HSRs), lack defined epidemiology.
  • Understanding ARs is crucial for prioritizing healthcare allergy safety initiatives.

Purpose of the Study:

  • To identify and characterize safety reports of allergic reactions.
  • To inform strategies for enhancing allergy safety in healthcare settings.

Main Methods:

  • Searched a decade of safety reports (2006-2016) from a major academic medical center.
  • Utilized 101 keywords related to allergic symptoms, treatments, and triggers.
  • Summarized data for ARs, HSRs, and side effect/toxicity reactions.

Main Results:

  • 10% of 9111 events were ARs (436 HSRs, 440 side effects/toxicities).
  • Common HSRs included cutaneous reactions (83%), shortness of breath (16%), anaphylaxis (14%), and angioedema (12%).
  • Drugs caused 81% of HSRs, notably antibiotics (beta-lactams, vancomycin), contrast agents, chemotherapeutics, and opioids. Nondrug causes included blood products, latex, and devices.

Conclusions:

  • A decade of safety reports revealed patterns in ARs, HSRs, and side effects/toxicities.
  • Healthcare allergy safety should address common and severe reactions, focusing on safe administration of implicated drugs (beta-lactams, vancomycin, contrast agents, chemotherapeutics, opioids).
  • Priority non-drug HSR culprits include blood products, latex, and devices.