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[(INDUCED MALARIA)].

A V Kondrashin, A M Baranova, L F Morozova

    Meditsinskaia Parazitologiia I Parazitarnye Bolezni
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    Summary
    This summary is machine-generated.

    Transfusion-induced malaria remains a significant public health issue. Current diagnostic methods for malaria are insufficient, necessitating the development of rapid, cost-effective tests to ensure blood donation safety.

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    Area of Science:

    • Public Health
    • Infectious Diseases
    • Hematology

    Background:

    • Transfusion-induced malaria poses a persistent threat in endemic regions.
    • Malaria parasites can survive in stored blood for up to three weeks at 2-6°C.
    • Sporadic cases of transfusion-transmitted malaria have been reported, with a notable decrease in recent decades.

    Purpose of the Study:

    • To review the current challenges and problems associated with transfusion-induced malaria.
    • To highlight the limitations of existing diagnostic methods for detecting malaria pathogens in blood donations.
    • To emphasize the need for developing improved diagnostic strategies for blood safety.

    Main Methods:

    • Literature review of transfusion-induced malaria cases and diagnostic approaches.
    • Analysis of historical data on malaria transmission through blood transfusion.
    • Discussion of current immunological and molecular diagnostic limitations.

    Main Results:

    • Malaria parasites remain viable in refrigerated blood, posing a risk for transfusion.
    • Existing diagnostic tests (immunological and molecular) do not achieve 100% pathogen detection.
    • A significant reduction in reported cases from 1958-1990 to 1991-2016 was observed.

    Conclusions:

    • Transfusion-induced malaria remains a critical concern for blood safety.
    • There is an urgent need for highly efficient, rapid, and low-cost diagnostic methods.
    • Improved diagnostics are essential to prevent malaria transmission via blood donation.