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Aquablation and transurethral resection of the prostate (TURP) both significantly improve urodynamic outcomes for men with bladder outlet obstruction. Both procedures demonstrated similar efficacy in reducing obstruction at six months.

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Area of Science:

  • Urology
  • Surgical Innovation
  • Lower Urinary Tract Symptoms

Background:

  • Benign prostatic hyperplasia (BPH) affects millions of men, leading to lower urinary tract symptoms.
  • Current surgical options for BPH include transurethral resection of the prostate (TURP), a widely used but potentially morbid procedure.
  • Aquablation therapy offers a novel, minimally invasive approach using waterjet technology for prostate tissue ablation.

Purpose of the Study:

  • To compare the urodynamic outcomes of Aquablation therapy versus TURP in patients with BPH.
  • To assess the efficacy of Aquablation in improving bladder outlet obstruction compared to TURP.

Main Methods:

  • A randomized controlled trial (RCT) comparing Aquablation and TURP.
  • Urodynamic parameters, including detrusor pressure at maximum flow rate (pDet@qmax) and Bladder Outlet Obstruction Index, were measured at baseline and 6 months post-procedure.
  • 66 patients underwent urodynamic studies.

Main Results:

  • Both Aquablation and TURP significantly reduced pDet@qmax from baseline (p < .0001).
  • No significant difference in the reduction of pDet@qmax was observed between the Aquablation and TURP groups (p = .8919).
  • Both treatments resulted in a substantial decrease in the proportion of patients with bladder outlet obstruction (from 79% to 22% for Aquablation, and 96% to 22% for TURP).

Conclusions:

  • Aquablation therapy provides comparable urodynamic improvements to TURP in treating bladder outlet obstruction.
  • Aquablation is a safe and effective alternative to TURP for BPH management.
  • Further research may explore long-term outcomes and patient-reported benefits.