Related Experiment Video
Updated: Jan 29, 2026

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography
Published on: January 11, 2020
Visual detection of fluoride ion based on ICT mechanism
Sutapa Sahu1, Yeasin Sikdar1, Riya Bag1
1Department of Chemistry, University of Calcutta, 92, A.P.C. Road, Kolkata, India.
A new chemosensor, H3NTS, enables rapid and precise fluoride (F-) detection. This sensor shows potential for real-world applications, including analyzing fluoride levels in toothpaste and paper strips.
Area of Science:
- Analytical Chemistry
- Materials Science
Background:
- Fluoride ion (F-) detection is crucial in various environmental and industrial applications.
- Development of selective and sensitive chemosensors is essential for accurate F- monitoring.
Purpose of the Study:
- To design and synthesize a novel chemosensor (H3NTS) for rapid and accurate F- detection.
- To evaluate the sensing capabilities of H3NTS for F- discrimination among other anions.
- To explore the potential of H3NTS in real-world sample analysis.
Main Methods:
- UV-Vis spectroscopy and Nuclear Magnetic Resonance (NMR) spectroscopy (1H, 13C) were employed for characterization.
- Computational calculations were performed to understand the sensing mechanism.
- Colorimetric assays were conducted to assess selectivity and sensitivity towards F-.
Main Results:
- The H3NTS probe demonstrated a selective colorimetric response to F- in acetonitrile.
- The detection limit for F- was found to be as low as 6 μM.
- A reversible colorimetric switch was achieved through sequential addition of F- and Ca2+ ions.
- H3NTS showed promising performance in analyzing F- in real samples like toothpaste and paper strips.
Conclusions:
- H3NTS serves as an effective colorimetric chemosensor for F- detection.
- The sensor exhibits high selectivity and sensitivity, with potential for practical applications.
- The reversible switching capability offers further advantages for F- sensing systems.
More Related Videos
06:21Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
Published on: May 10, 2024
11:04Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
Published on: September 7, 2019
Related Concept Videos
Ions as Acids and Bases
Salts are ionic compounds composed of cations and anions, either of which may be capable of undergoing an acid or base ionization reaction with water. Aqueous salt solutions, therefore, may be acidic, basic, or neutral, depending on the relative acid-base strengths of the salt’s constituent ions. For example, dissolving the ammonium chloride in water results in its dissociation, as described by the equation:
Mechanically-gated Ion Channels
Ions and Ionic Charges
Trends in Lattice Energy: Ion Size and Charge
Common Ion Effect
Ligand-Gated Ion Channel Receptor: Gating Mechanism