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Updated: Jan 29, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Group-Based Individualized Comprehensive Core Stability Intervention Improves Balance in Persons With Multiple
Ellen Christin Arntzen1, Bjørn Kåre Straume2, Francis Odeh3
1Nordland Hospital Trust, Department of Physical Therapy, 8028 Bodø, Norway.
A 6-week core stability program significantly improved balance and trunk control in individuals with multiple sclerosis (MS) compared to standard care, with lasting effects observed long-term. This intervention offers an effective physical therapy approach for MS patients.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Physical Therapy
Background:
- Individuals with multiple sclerosis (MS) frequently experience impaired balance and trunk control.
- Effective interventions are crucial for managing these functional deficits in MS patients.
Purpose of the Study:
- To compare the immediate and long-term effects of a 6-week comprehensive core stability intervention (GroupCoreDIST) against standard care.
- To assess the impact on balance and trunk control in individuals with MS.
Main Methods:
- A prospective, assessor-masked, randomized controlled trial involving 80 participants with MS (Expanded Disability Status scores 1-6.5).
- Participants were randomized to either the GroupCoreDIST intervention (n=40) or standard care (n=40).
- Assessments of trunk impairment, balance, and patient-reported outcomes were conducted at baseline and at weeks 7, 18, and 30.
Main Results:
- The GroupCoreDIST intervention demonstrated significant improvements in Trunk Impairment Scale-Norwegian Version and Mini Balance Evaluation Systems Test scores at all post-intervention time points (weeks 7, 18, 30) compared to standard care.
- Patient Global Impression of Change-Balance scores also showed significant improvements favoring the GroupCoreDIST group at 7, 18, and 30 weeks.
- The study included 79 participants in the intention-to-treat analysis, with no significant between-group differences noted for physical therapy volume.
Conclusions:
- A 6-week GroupCoreDIST intervention effectively improved balance and trunk control in individuals with MS in both the short and long term.
- This core stability program represents a valuable addition to physical therapy strategies for managing functional impairments in the MS population.
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