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Updated: Jan 29, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Device Programming for His Bundle Pacing.

Haran Burri1, Daniel Keene2,3, Zachary Whinnett2

  • 1Cardiology Department, University Hospital of Geneva, Switzerland (H.B.).

Circulation. Arrhythmia and Electrophysiology
|February 7, 2019
PubMed
Summary
This summary is machine-generated.

Permanent His bundle pacing is gaining traction due to improved implantation tools. This article offers programming recommendations for His bundle pacing to optimize therapy and ensure patient safety.

Keywords:
bundle of Hiscardiac pacemaker, artificialcardiac resynchronization therapydefibrillatorspatient safety

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Area of Science:

  • Cardiology
  • Medical Devices
  • Electrophysiology

Background:

  • Permanent His bundle pacing, a technique for cardiac rhythm management, has been available for nearly two decades.
  • Wider adoption is recent, driven by advancements in implant procedure tools.
  • Programming implantable pulse generators for His bundle pacing presents unique challenges.

Purpose of the Study:

  • To provide practical recommendations for programming His bundle pacing systems.
  • To guide clinicians in achieving optimal therapeutic outcomes.
  • To ensure patient safety during His bundle pacing therapy.

Main Methods:

  • This article reviews current knowledge and clinical experience with His bundle pacing.
  • It synthesizes information to formulate practical programming guidelines.
  • Recommendations are based on established electrophysiological principles and clinical observations.

Main Results:

  • His bundle pacing requires specific programming configurations distinct from traditional pacing.
  • Current implantable pulse generators may need specialized settings for optimal His bundle pacing.
  • Consideration of lead placement and patient-specific electrograms is crucial.

Conclusions:

  • Effective programming is essential for successful His bundle pacing.
  • Adherence to practical recommendations can enhance therapy delivery and patient safety.
  • Further development of pacing systems tailored for His bundle pacing may be beneficial.