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08:20
In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
Published on: May 1, 2020
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Angiosarcoma with Synchronous Cutaneous and Small Bowel Involvement: A Report of a Rare Presentation
Erin Reis1, Kadra Kalamaha1, Hongchen Jia2
1Internal Medicine, University of North Dakota School of Medicine and Health Sciences, Bismarck, USA.
Cureus
|February 7, 2019
Summary
This case study details a rare angiosarcoma diagnosis in a 75-year-old female, highlighting its multi-focal spread and treatment with radiation, paclitaxel, and bevacizumab.
Area of Science:
- Oncology
- Vascular Neoplasms
Background:
- Angiosarcomas are rare soft tissue sarcomas originating from vascular endothelium, accounting for about 2% of all sarcomas.
- This study focuses on a unique and aggressive presentation of angiosarcoma.
Observation:
- A 75-year-old female presented with a distinctive purple nodular rash on her face.
- Further investigation revealed multi-focal angiosarcoma involving the face, duodenum, lungs, liver, and bone.
Findings:
- The patient was diagnosed with angiosarcoma with widespread metastatic involvement.
- Treatment involved a combination of radiation therapy, paclitaxel, and bevacizumab.
- Co-existing liver cirrhosis and gastric antral vascular ectasia (GAVE) were noted.
Implications:
- This case highlights an unusual clinical presentation of angiosarcoma.
- The study discusses the complex interplay between co-morbidities (liver cirrhosis, GAVE) and angiosarcoma development and treatment.
- Effective management strategies for rare, multi-focal angiosarcomas are explored.
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