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Amyloid β perturbs elevated heme flux induced with neuronal development

Chantal Vidal1, Kelly Daescu1, Keely E Fitzgerald1

  • 1Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, USA.

Alzheimer'S & Dementia (New York, N. Y.)
|February 7, 2019
PubMed
Summary

Altered heme metabolism, specifically reduced heme degradation and HO-2 levels, is an early indicator in Alzheimer's disease (AD) pathogenesis. This finding highlights heme's role in AD progression.

Keywords:
Alzheimer's diseaseAmyloid βHemeHeme degradationHeme oxygenase

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