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Published on: August 6, 2019
Pholiotone A, a new polyketide derivative from Pholiota sp
Yingchao He1, Renlei Wang2, Bin Huang2
1Clinical Medical College of Fujian Provincial Hospital, Fujian Medical University/Fujian provincial Hospital, Fuzhou, People's Republic of China.
Abstract:
Pholiotone A (1), a new polyketide derivative, with tetrahydrobenzofuran-4(2H)-one skeleton, together with four known compounds, trichodermatides A (2) and B (3) and koninginins B (4) and E (5), were isolated from the crude extract of Pholiota sp. The structures of all the isolated compounds were determined mainly by NMR experiments, the modified Mosher method and electronic circular dichroism (ECD) calculations. The antifungal and cytotoxicity of all isolates were evaluated.
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