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Quantitative Assessment of Thyroid Glands in Healthy Children With Shear Wave Elastography

Emine Uysal1, Mehmet Öztürk

  • 1Department of Radiology, Selçuk University Faculty of Medicine, Konya, Turkey.

Ultrasound Quarterly
|February 7, 2019
PubMed

Insights

This study established reference values for thyroid elasticity and shear wave velocity in healthy children, providing a baseline for diagnosing pediatric thyroid conditions.

Area of Science:

  • Pediatric endocrinology
  • Medical imaging
  • Rheology

Background:

  • Establishing normative data for thyroid gland biomechanical properties in children is crucial for accurate disease diagnosis.
  • Previous research has not comprehensively defined reference values for shear wave speed and Young's modulus in healthy pediatric thyroid glands.

Purpose of the Study:

  • To determine reference values for shear wave speed (m/s) and Young's modulus (kPa) in the normal thyroid glands of healthy children.
  • To establish a baseline for the investigation of pediatric thyroid diseases using quantitative elasticity measurements.

Main Methods:

  • A prospective study involving 107 healthy children (ages 3-17) without thyroid disease.
  • Measurements of shear wave velocity and Young's modulus were taken from three sites in both thyroid lobes and averaged.
  • Data on age, sex, weight, height, and body mass index (BMI) were collected for all participants.

Main Results:

  • Median elasticity values were 6.38 kPa (right lobe) and 8.81 kPa (left lobe).
  • Median shear wave velocities were 1.45 m/s (right lobe) and 1.69 m/s (left lobe).
  • A positive correlation was observed between right thyroid lobe elasticity and shear wave velocity with age, BMI, and lobe volume; no significant correlation was found for the left lobe.

Conclusions:

  • This study provides essential reference values for thyroid gland elasticity and shear wave velocity in healthy children.
  • These normative data serve as a critical baseline for identifying and evaluating thyroid abnormalities in pediatric populations.

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