Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Physiology of Smell and Olfactory Pathway

Physiology of Smell and Olfactory Pathway

Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...

Olfactory Receptors: Location and Structure

Olfactory Receptors: Location and Structure

The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...

Appendicitis-II: Diagnostic Studies and Management

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...

Myasthenia Gravis: Diagnostic Tests

Myasthenia Gravis: Diagnostic Tests

Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...

Asthma-IV: Diagnostic and Management

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

Pericarditis II: Clinical Features and Diagnostic Tests

Pericarditis II: Clinical Features and Diagnostic Tests

Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Interprofessional communication in the ambulatory health sector in Germany: a multi-perspective cross-sectional study (<i>interprof</i> HOME).

Journal of interprofessional care·2025

Same author

[Specialized trauma surgery: do we need it at all?]

Unfallchirurgie (Heidelberg, Germany)·2024

Same author

Future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium-an overview.

HNO·2023

Same author

Study protocol P-MAPS: microbiome as predictor of severity in acute pancreatitis-a prospective multicentre translational study.

BMC gastroenterology·2021

Same author

[Future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium-an overview].

HNO·2021

Same author

Factors associated with relevant olfactory recovery after olfactory training: a retrospective study including 601 participants.

Rhinology·2021

Search research articles

Related Experiment Video

Updated: Jan 29, 2026

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Published on: April 1, 2019

[Diagnostics and treatment of olfactory dysfunction].

M Damm^1,2, L Schmitl³, C A Müller⁴

¹HNO-Heilkunde Köln, Aachener Str. 407, 50933, Köln, Deutschland. Prof.Damm@hno-heilkunde-koeln.de.

|February 7, 2019

Summary

This summary is machine-generated.

Dysosmia diagnosis decreased significantly, possibly due to more critical evaluation. Topical steroids are effective for sinonasal smell disorders, and olfactory training is increasingly used and recommended.

Keywords:

Anosmia Epidemiology Hyposmia Sinunasal Steroids

More Related Videos

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Author Spotlight: Improving Anesthesia Protocols for Enhanced Mouse Acupuncture Research

Author Spotlight: Improving Anesthesia Protocols for Enhanced Mouse Acupuncture Research

Published on: December 8, 2023

Related Experiment Videos

Last Updated: Jan 29, 2026

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Published on: April 1, 2019

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Author Spotlight: Improving Anesthesia Protocols for Enhanced Mouse Acupuncture Research

Author Spotlight: Improving Anesthesia Protocols for Enhanced Mouse Acupuncture Research

Published on: December 8, 2023

Area of Science:

Otorhinolaryngology
Olfactory Dysfunction Research

Background:

Dysosmia is a common otorhinolaryngology disorder with limited epidemiological data.
Standardization of treatment strategies for olfactory disorders is lacking.

Purpose of the Study:

Evaluate the frequency of olfactory disorder causes and therapeutic approaches in German-speaking ENT departments.
Compare current findings with a 2000 survey and conduct a systematic review of treatments.

Main Methods:

A two-page survey on olfactory dysfunction was distributed to ENT departments in German-speaking countries in 2010.
A systematic literature review was performed using PubMed, Cochrane Library, and guidelines.

Main Results:

A 52% decrease in dysosmia diagnosis frequency was observed.
Corticosteroids (topical and systemic) and systemic antibiotics were the most common treatments.
Topical steroids show a small to medium effect in sinonasal smell disorders.

Conclusions:

Decreased patient numbers may reflect more critical diagnosis rather than reduced prevalence.
Olfactory training use increased significantly (from <6% to 23%).
Topical steroids are evidence-based for sinonasal dysosmia; smell training is safe and effective for post-infectious/traumatic cases.