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Related Concept Videos

Breathing01:05

Breathing

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The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
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Modern Molecular Taxonomy01:29

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Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
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Mechanism of Breathing I: Inspiration01:30

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Introduction to Inspiration: The Respiratory System in Action
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Mechanism of Breathing II: Expiration01:23

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Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

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Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
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Mechanism of Breathing III: The Accessory Muscles01:21

Mechanism of Breathing III: The Accessory Muscles

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The Role of Accessory Muscles in the Respiratory System
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Related Experiment Video

Updated: Jan 29, 2026

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry
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Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry

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[Modern breath analysis].

L M Wirtz1, S Kreuer2, T Volk2

  • 1Center of Breath Research (CBR); Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum des Saarlandes, Kirrberger Straße 100, Gebäude 57, 66424, Homburg (Saar), Deutschland. lukas.wirtz@uks.eu.

Medizinische Klinik, Intensivmedizin Und Notfallmedizin
|February 7, 2019
PubMed
Summary
This summary is machine-generated.

Breath analysis offers a non-invasive method for diagnosing critical conditions and monitoring drugs like propofol in intensive care. Future applications include early detection of sepsis, hemorrhage, and organ dysfunction through exhaled volatile organic compounds.

Keywords:
Breath analysisDrug monitoringExhaled air analysisIntensive careVolatile biomarkers

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Area of Science:

  • Intensive care medicine
  • Clinical diagnostics
  • Analytical chemistry

Background:

  • Exhaled air analysis is a safe bedside diagnostic method.
  • Modern breath analysis detects trace volatile organic compounds.
  • Research focuses on drug monitoring and disease diagnosis.

Purpose of the Study:

  • Discuss current breath analysis research.
  • Highlight relevance to intensive care medicine.

Main Methods:

  • Literature search on PubMed.
  • Keywords: breath analysis, volatile organic compounds, critically ill, drug monitoring, propofol, heart failure, pneumonia, ARDS, renal failure, liver failure, sepsis, hemorrhage.

Main Results:

  • Propofol levels accurately measured in exhaled air.
  • Organ dysfunction (heart, lung, kidney, liver) alters breath composition.
  • Animal studies show potential for detecting sepsis, hemorrhage, and lung injury.

Conclusions:

  • Breath analysis can non-invasively monitor drugs.
  • Future diagnostics for critical care conditions are possible.
  • Potential for early detection of sepsis, hemorrhage, and ARDS.