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Related Experiment Video

Updated: Jan 29, 2026

Purification of a High Molecular Mass Protein in Streptococcus mutans
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Streptococcus mutans detection in saliva and colostrum samples.

Camilla Beatriz da Silva1, Marcelly Milhomem Mendes1, Bárbara Rocha Rodrigues1

  • 1Universidade de Uberaba, Uberaba, MG, Brazil.

Einstein (Sao Paulo, Brazil)
|February 7, 2019
PubMed
Summary
This summary is machine-generated.

Streptococcus mutans was detected in some neonatal colostrum and saliva, with maternal saliva showing higher prevalence. Dental hygiene and treatment impact S. mutans presence in mothers and newborns.

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Area of Science:

  • Microbiology
  • Neonatal Health
  • Oral Health

Background:

  • Streptococcus mutans is a primary agent of dental caries.
  • Vertical transmission of S. mutans from mother to child is a known pathway.
  • Understanding S. mutans colonization in neonates is crucial for early oral health interventions.

Purpose of the Study:

  • To investigate the presence of Streptococcus mutans in neonatal colostrum and saliva.
  • To compare S. mutans detection in neonates with its presence in maternal saliva.
  • To explore factors influencing S. mutans colonization in early life.

Main Methods:

  • Polymerase chain reaction (PCR) was employed for bacterial detection.
  • Samples were collected from 43 healthy mothers and their newborns following elective Cesarean section.
  • Colostrum, maternal saliva, and neonatal saliva were analyzed for S. mutans genetic material.

Main Results:

  • S. mutans was identified in approximately 16% of colostrum samples.
  • Prevalence of S. mutans in maternal and neonatal saliva was 49% and 30%, respectively.
  • A positive correlation was observed between S. mutans detection in maternal and neonatal saliva. Dental treatment during pregnancy and tooth brushing frequency influenced detection rates.

Conclusions:

  • While S. mutans is infrequently found in colostrum, its presence in neonatal saliva may indicate prenatal exposure.
  • Maternal oral hygiene practices and dental care during pregnancy appear to affect S. mutans colonization in mothers and potentially neonates.
  • Further research into early S. mutans transmission and prevention strategies is warranted.