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RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types

Gianni Monaco1, Bernett Lee2, Weili Xu2

  • 1Singapore Immunology Network (SIgN), Agency for Science Technology and Research, Biopolis, 8A Biomedical Grove, 138648, Singapore, Singapore; Integrative Genomics of Ageing Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool L78TX, UK; Department of Biomedicine, University Hospital and University of Basel, 4031 Basel, Switzerland.

Cell Reports
|February 7, 2019
PubMed

Keywords:
RNA-seqdeconvolutionflow cytometrygene moduleshousekeepingimmune systemmRNA abundancemRNA compositionmRNA heterogeneitytranscriptome

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