Related Experiment Video
Updated: Jan 29, 2026

03:40
Three-Dimensional Printing of a Complex Aortic Anomaly
Published on: November 1, 2018
7.1K
Reconstructive surgery for Ebstein anomaly: three decades of experience
Kevin M Veen1, Mostafa M Mokhles1, Jolien W Roos-Hesselink2
1Department of Cardiothoracic Surgery, Erasmus MC, Rotterdam, Netherlands.
Summary
Tricuspid valve repair for Ebstein anomaly using vertical plication demonstrates excellent long-term outcomes. Cone repair is particularly effective, showing less tricuspid regurgitation progression and durable valve function.
Area of Science:
- Cardiovascular Surgery
- Congenital Heart Disease
- Valvular Heart Disease
Background:
- Ebstein anomaly is a rare congenital heart defect affecting the tricuspid valve.
- Surgical repair aims to restore valve function and improve patient outcomes.
- Vertical plication with deattachment and reattachment of the tricuspid valve has been employed since 1988.
Purpose of the Study:
- To describe the characteristics of patients undergoing tricuspid valve repair for Ebstein anomaly.
- To evaluate the long-term outcomes of this surgical technique.
- To compare the effectiveness of different repair methods, specifically Carpentier-Chauvaud and Cone repair.
Main Methods:
- Retrospective collection of data from patients operated on between 1988 and 2016.
- Kaplan-Meier analysis for survival and freedom from reoperation.
- Mixed models for longitudinal analysis of clinical and echocardiography data.
Main Results:
- 36 patients (mean age 25.4 years) underwent repair, with 58% Carpentier-Chauvaud and 42% Cone repair.
- 25-year survival was 97% ± 3%, with freedom from reoperation at 80% ± 8%.
- Cone repair was associated with less tricuspid regurgitation progression compared to rigid ring repair.
Conclusions:
- Tricuspid valve repair for Ebstein anomaly offers low mortality and morbidity.
- The repair technique provides acceptable reoperation rates and excellent long-term valve function.
- Cone repair is a durable and effective method for treating Ebstein anomaly.
Related Concept Videos
What is an Experiment?
17.9K
An experiment is a planned activity carried out under controlled conditions. The purpose of an experiment is to investigate the relationship between two variables. When one variable causes change in another, we call the first variable the explanatory or independent variable. The affected variable is called the response or dependent variable. In a randomized experiment, the researcher manipulates values of the explanatory variable and measures the resulting changes in the response variable. The...
17.9K
Thomson's e/m Experiment
6.7K
In a beam of charged particles created by a heated cathode, the particles move at different speeds. However, many applications need a beam with uniform particle speeds. An arrangement known as a velocity selector uses electric and magnetic fields to pick particles with a particular speed from the beam.
A particle with charge q, speed v, and mass m enters an area from the top, where the magnetic and electric fields are perpendicular both to the particle's motion and to one another. The magnetic...
A particle with charge q, speed v, and mass m enters an area from the top, where the magnetic and electric fields are perpendicular both to the particle's motion and to one another. The magnetic...
6.7K
Reconstruction of Signal using Interpolation
726
Signal processing techniques are essential for accurately converting continuous signals to digital formats and vice versa. When a continuous signal is sampled with a period T, the resulting sampled signal exhibits replicas of the original spectrum in the frequency domain, spaced at intervals equal to the sampling frequency. To handle this sampled signal, a zero-order hold method can be applied, which creates a piecewise constant signal by retaining each sample's value until the next...
726
Controls in Experiments
16.9K
When conducting an experiment, it is crucial to have control to reduce bias and accurately measure the dependent variables. It also marks the results more reliable. Controls are elements in an experiment that have the same characteristics as the treatment groups but are not affected by the independent variable. By sorting these data into control and experimental conditions, the relationship between the dependent and independent variables can be drawn. A randomized experiment always includes a...
16.9K
Randomized Experiments
9.0K
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Simple randomization
Simple...
9.0K
Crossover Experiments
4.6K
Crossover experiments, also called the repeated-measurements design, is a study design in which all experimental units are exposed to all treatments in different periods. Crossover experiments are generally used in psychology, the pharmaceutical industry, agriculture, and medicine.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
4.6K

