Related Experiment Video
Updated: Jan 29, 2026
08:31
Fabrication of Engineered Vascular Flaps Using 3D Printing Technologies
Published on: May 19, 2022
4.5K
Pharmaceutical Product Development Exploiting 3D Printing Technology: Conventional to Novel Drug Delivery System
Md Shoaib Alam1, Ayesha Akhtar2, Iftikhar Ahsan1
1Research and Development, Jamjoom Pharmaceuticals, Jeddah 21442, Saudi Arabia.
Current Pharmaceutical Design
|February 8, 2019
Summary
3D printing is revolutionizing medicine by enabling personalized treatments tailored to individual patient needs. This technology offers enhanced accuracy and effectiveness, transforming drug delivery and manufacturing processes.
Area of Science:
- Pharmaceutical Science
- Biotechnology
- Materials Science
Background:
- 3D printing offers personalized pharmaceutical treatments based on patient-specific factors like age, weight, and pharmacogenetics.
- This technology addresses challenges in conventional medicine, presenting a modern alternative for drug formulation and delivery.
- The US FDA approved the first 3D printed tablet in 2015, highlighting the growing significance of this innovation.
Purpose of the Study:
- To review strategies for managing 3D printing methods in pharmaceutical manufacturing.
- To introduce the evolution of drug delivery systems from conventional to novel 3D printed approaches.
- To summarize the role of 3D printing in advancing medicine and drug delivery.
Main Methods:
- Review of current literature on 3D printing techniques in pharmaceutical applications.
- Analysis of drug manufacturing processes in the context of 3D printing.
- Exploration of technological advancements in medicine and drug delivery.
Main Results:
- 3D printing facilitates high-throughput, versatile, and automated fabrication of controlled drug delivery systems.
- The technology enables precise spatial control and the creation of complex hierarchical structures.
- Implementation of 3D printing plays a pivotal role in the development and delivery of advanced drug formulations.
Conclusions:
- 3D printing technology allows for flexible manufacturing and design of composite products for personalized medicine.
- Personalized medicine improves drug safety and minimizes toxicity by optimizing dosage for individuals.
- 3D printing is a key enabler of programmable and personalized therapeutic solutions.
Related Concept Videos
01:28Factors Influencing Drug Absorption: Pharmaceutical Parameters
515
Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
515
01:16Drug Delivery: Overview
843
The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
843
01:16Drug Product Stability
258
The long-term stability of drug products is critical to ensuring their quality, safety, and effectiveness over time. Stability directly influences a product's ability to maintain its intended characteristics, ensuring it performs as expected during its intended shelf life. Key attributes such as drug potency, impurities, dissolution, and other physicochemical measures of performance are tested to assess stability. These parameters indicate how well the product retains its quality over time and...
258
01:26Pharmaceutical Equivalents
201
As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
201
01:18Drug Delivery: Enteral Route
1.7K
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
1.7K
01:29Drug Delivery: Parenteral Route
1.7K
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
1.7K