Related Experiment Video
Updated: Jan 29, 2026
03:26
Fixation of Ultrasound Transducers for Spinal Cord Neuromodulation in Mice
Published on: August 1, 2025
762
Neurologic Injury After Sacral Neuromodulation
Angela S Yuan, Jorge L Almodovar1, Elisabeth Erekson
1Department of Neurology, Dartmouth-Hitchcock, Manchester.
Female Pelvic Medicine & Reconstructive Surgery
|February 8, 2019
Summary
Neurologic injury from sacral nerve stimulation (SNS) infections is rare. Prompt diagnosis and treatment of epidural infections are crucial to prevent persistent leg weakness and pain after SNS procedures.
Area of Science:
- Neurology
- Infectious Diseases
- Surgical Complications
Background:
- Sacral nerve stimulation (SNS) is a treatment for fecal incontinence.
- Neurologic injury is a rare complication of SNS.
- Infection is a potential cause of neurologic damage following SNS.
Observation:
- A case report details a patient with Crohn's disease and fecal incontinence who developed a wound infection after SNS implantation.
- The infection led to device explantation and subsequent epidural infection.
- The patient experienced leg pain and weakness, indicative of neurologic deficits.
Findings:
- The patient underwent urgent evaluation and treatment for epidural infection.
- Despite treatment, the patient had persistent neurologic deficits six months post-infection.
- This case highlights the potential for severe neurologic sequelae from infection after SNS.
Implications:
- Clinicians should consider epidural infection in patients presenting with fever, leg pain, and neurologic deficits post-SNS.
- Early recognition and management of infection are critical to mitigate neurologic damage.
- This underscores the importance of vigilance for infectious complications following neuromodulation procedures.
Related Concept Videos
01:22Burn Injuries
4.4K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
4.4K
01:22Acute Kidney Injury I: Introduction
680
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
680
01:29Acute Kidney Injury II: Pathophysiology
1.1K
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
1.1K
01:22Acute Kidney Injury VI: Nursing Management
441
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
441
01:20Acute Kidney Injury V: Interprofessional Care
347
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
347
01:22Pathophysiology of Peptic Ulcer Disease: Injurious Factors
1.2K
Peptic ulcers are sores on the stomach's inner lining and the upper small intestine, which are the result of disruptions in the mucosal layer that houses parietal cells which produce gastric acid, and chief cells which secrete pepsinogen.
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
1.2K