Related Experiment Video
Updated: Jan 29, 2026

An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
A new technique of managing paravalvular leak using a folding pericardium patch
Tingting Tao1, Junnan Zheng1, Yiming Ni1
1Department of Cardiothoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
A novel technique using a folding pericardium patch effectively manages paravalvular leakage (PVL) after prosthetic valve replacement, avoiding repeat surgery. This method shows promise for intraoperative PVLs, particularly in aortic valve procedures.
Area of Science:
- Cardiovascular Surgery
- Medical Devices
- Surgical Techniques
Background:
- Paravalvular leakage (PVL) is a known complication following prosthetic valve replacement surgery.
- Current management strategies may involve repeat valve replacement, which carries significant risks.
- Small to moderate PVLs, often sized one to two stitches, present a specific challenge.
Purpose of the Study:
- To introduce and evaluate a new technique for managing intraoperative paravalvular leakage.
- To present a less invasive alternative to re-operation for PVL.
- To demonstrate the efficacy of a folding pericardium patch for PVL closure.
Main Methods:
- Development of a novel surgical technique utilizing a folding pericardium patch.
- Application of the technique in patients experiencing intraoperative paravalvular leakage.
- Focus on cases involving the aortic valve position.
Main Results:
- The folding pericardium patch technique was successfully applied in at least four cases.
- All treated cases demonstrated positive outcomes, indicating successful closure of PVLs.
- The technique proved effective in managing intraoperative PVLs without necessitating re-operation.
Conclusions:
- The folding pericardium patch technique offers a viable and effective solution for intraoperative paravalvular leakage.
- This method presents a significant advantage by avoiding the need for a second valve replacement.
- It is a promising alternative management strategy, especially for PVLs in the aortic position.
More Related Videos
Related Concept Videos
Molecular Chaperones and Protein Folding
The...
Protein Folding
Protein Folding
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
Impression Management Techniques I: Managing Appearances
Impression Management Techniques II: Ingratiation
Stress Prevention and Stress Management Techniques II
Type A Personality: Driven and Easily Stressed
Individuals with Type A personalities are often highly competitive and ambitious and operate with a strong sense of urgency. Commonly labeled as...

