Related Experiment Video
Updated: Jan 29, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Transvenous embolization of arteriovenous malformations
George Zaki Ghali1, Michael George Zaki Ghali2, Emil Zaki Ghali3
1United States Environmental Protection Agency, Arlington, VA 22202, USA; Department of Toxicology, Purdue University, West Lafayette, IN 47907, USA.
Transvenous embolization offers a safe and effective alternative for treating arteriovenous malformations (AVMs), potentially achieving AVM cure alone. This approach directly targets the AVM nidus, overcoming limitations of the traditional transarterial route.
Area of Science:
- Interventional Radiology
- Vascular Surgery
- Neurology
Background:
- Arteriovenous malformations (AVMs) are often treated with multimodal approaches, including pre-operative embolization.
- Transarterial embolization is common, but the transvenous route has been historically avoided due to concerns about venous occlusion and hemorrhage.
Purpose of the Study:
- To review the efficacy and safety of the transvenous approach for AVM embolization.
- To discuss the advantages of transvenous embolization over the transarterial route.
- To highlight innovations in endovascular strategies for improved AVM obliteration.
Main Methods:
- Review of existing literature and clinical series on transvenous AVM embolization.
- Discussion of endovascular strategies and techniques.
- Analysis of outcomes related to AVM obliteration rates.
Main Results:
- The transvenous approach offers distinct advantages for AVM treatment, especially when the transarterial route is not feasible.
- Several studies have demonstrated the efficacy and safety of transvenous embolization.
- Direct targeting of the AVM nidus is facilitated by the transvenous route, with controlled arterial inflow enhancing embolisate penetration.
Conclusions:
- Transvenous embolization is a viable and effective method for treating AVMs, offering an alternative to or adjunct with other therapies.
- Advances in endovascular techniques have improved obliteration rates.
- The transvenous route can achieve AVM cure, challenging the traditional reliance on multimodal treatment.
Related Concept Videos
Pulmonary Embolism I: Introduction
Pulmonary Embolism III: Nursing Management
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

