Related Experiment Video
Updated: Jan 29, 2026

Natural Product Discovery with LC-MS/MS Diagnostic Fragmentation Filtering: Application for Microcystin Analysis
Published on: May 31, 2019
Microcystin-LR disturbs testicular development of giant freshwater prawn Macrobrachium rosenbergii
Yingying Zhang1, Hang Zhuang1, Hui Yang1
1College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, China.
Abstract:
Microcystins (MCs) are produced by cyanobacterial blooms and known for their hepatotoxicity. They could cause serious damage to the reproduction of higher vertebrate mice and fish. However, few studies have focused on the reproductive toxicity of MCs to invertebrates. Giant freshwater prawn Macrobrachium rosenbergii are highly cultivated in China. During their breeding process, M. rosenbergii are often infested by cyanobacteria blooms. In the present study, to investigate the toxic effect of MCs on the testicular development of M. rosenbergii. Male M. rosenbergii were exposed to environmental relevant concentration of MC-LR for 1, 2 and 3 weeks. Results showed that MC-LR entered M. rosenbergii testis, down-regulated hemolymph testosterone (T) levels, and damaged testicular germ cells, mitochondria and cell junctions, and inhibited testicular development. Moreover, MC-LR could significantly induce the expression of gonadal development related genes in testis and eyestalk). The present results indicate that MC-LR can disrupt the testicular development of M. rosenbergii by affecting T levels and gonadal development related genes in the testis and eyestalk.
More Related Videos
07:22Standardizing a Non-Lethal Method for Characterizing the Reproductive Status and Larval Development of Freshwater Mussels Bivalvia: Unionida
Published on: October 4, 2019
10:05Development and Identification of a Novel Subpopulation of Human Neutrophil-derived Giant Phagocytes In Vitro
Published on: January 25, 2017
Related Concept Videos
Ecological Disturbance
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Sustainable Development
Development of the Lymphatic System
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
Language Development
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...