Related Experiment Video

Updated: Jan 29, 2026

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

1.5K

The HAS-BLED Score is Associated With Major Bleeding in Patients After Cardiac Surgery

Gianluca Santise1, Saverio Nardella1, Francesco Migliano1

  • 1Cardiothoracic Surgery Unit, Sant'Anna Hospital, Catanzaro, Italy.

Journal of Cardiothoracic and Vascular Anesthesia
|February 9, 2019
PubMed

Insights

The HAS-BLED score predicts major bleeding risk in cardiac surgery patients. A higher score indicates an increased likelihood of late bleeding events post-surgery.

Area of Science:

  • Cardiology
  • Surgical Outcomes
  • Hemorrhagic Risk Assessment

Background:

  • The Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile international normalized ratio, Elderly, Drugs/alcohol (HAS-BLED) score is established for predicting bleeding risk in atrial fibrillation patients on anticoagulation.
  • The applicability of the HAS-BLED score in predicting bleeding events following cardiac surgery remains to be fully elucidated.

Purpose of the Study:

  • To investigate the association between the HAS-BLED score and the occurrence of major bleeding events in patients undergoing cardiac surgery.
  • To determine if the HAS-BLED score can serve as a predictive tool for post-cardiac surgery bleeding complications.

Main Methods:

  • A prospective, single-center, nonrandomized study involving 1,173 consecutive adult patients undergoing standard cardiac operations.
  • Major bleeding events were defined per Bleeding Academy Research Consortium criteria and categorized as early (≤48 hours) or late (>48 hours to 90 days postoperatively).
  • Patient follow-up extended for 120 days post-discharge, including outpatient visits and phone calls.

Main Results:

  • A total of 29 patients (2.5%) experienced early major bleeding, and 34 patients (2.9%) experienced late major bleeding.
  • Univariate and multivariable analyses revealed no significant association between the HAS-BLED score and early bleeding.
  • The HAS-BLED score was significantly associated with an increased risk of late major bleeding events (OR 1.67; 95% CI 1.19-2.35).

Conclusions:

  • The HAS-BLED score is a significant predictor of major bleeding risk in the late postoperative period following cardiac surgery.
  • This finding suggests that the HAS-BLED score could aid in tailoring anticoagulation and antiplatelet therapy strategies for cardiac surgical patients.
  • Utilizing the HAS-BLED score may help optimize perioperative management to mitigate bleeding risks in this patient population.
Abstract

Keywords:
HAS-BLEDatrial fibrillationbleedingcardiac surgeryrisk score

More Related Videos

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery04:48

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery

Published on: November 28, 2018

8.4K
A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

663

Related Concept Videos

Bleeding in Fresh Concrete01:22

Bleeding in Fresh Concrete

Bleeding in fresh concrete occurs when water from the mix rises to the surface. This happens because the mix's solid components fail to retain all the water as they settle, leading to separation where water collects at the top. The severity of bleeding can be measured by assessing the total settlement or by noting the decrease in height per unit height of concrete.
Bleeding can cause several issues in the concrete structure. Sometimes, the rising water gets trapped beneath large aggregate...
573
Introduction to z Scores01:06

Introduction to z Scores

A z score (or standardized value) is measured in units of the standard deviation. It tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a zero z score. It is important to note that the mean of the z scores is zero, and the standard deviation is one.
z scores...
11.2K
Introduction to z Scores01:05

Introduction to z Scores

A z score (or standardized value) is measured in units of the standard deviation. It indicates how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a zero z score. It is important to note that the mean of the z scores is zero, and the standard deviation is one.
z scores...
1.3K
z Scores and Area Under the Curve01:17

z Scores and Area Under the Curve

z scores are the standardized values obtained after converting a normal distribution into a standard normal distribution. A z score is measured in units of the standard deviation. The z score tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a z score of...
19.6K
Major Organs of the Digestive System01:19

Major Organs of the Digestive System

The digestive system is responsible for the ingestion of food, secretion of enzymes, mixing and digesting food, absorption of the nutrients and defecation. The human digestive system consists of two major parts: the gastrointestinal tract and the accessory digestive organs.
Gastrointestinal tract:
9.3K
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
1.9K