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Clinical Practice Guideline for Emergency Department Procedural Sedation With Propofol: 2018 Update

Kelsey A Miller1, Gary Andolfatto2, James R Miner3

  • 1Division of Emergency Medicine, Boston Children's Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, MA.

Annals of Emergency Medicine
|February 9, 2019
PubMed

Insights

This updated guideline provides evidence-based recommendations for propofol administration in emergency department procedural sedation. It addresses pediatric considerations and new research for safer sedation practices.

Area of Science:

  • Emergency Medicine
  • Pharmacology
  • Clinical Practice Guidelines

Background:

  • The 2007 advisory on propofol for procedural sedation requires updating.
  • New research and unique pediatric considerations necessitate guideline revision.

Purpose of the Study:

  • To update the evidence-based clinical practice guideline for propofol administration.
  • To provide comprehensive guidance for emergency department procedural sedation.

Main Methods:

  • Review of substantial new research.
  • Inclusion of unique considerations for pediatric populations.
  • Synthesis of evidence for clinical recommendations.

Main Results:

  • Updated recommendations on indications and contraindications for propofol use.
  • Guidance on personnel, monitoring, and dosing.
  • Information on coadministered medications and adverse events.

Conclusions:

  • Revised guideline ensures safe and effective propofol sedation in emergency departments.
  • Addresses specific needs of pediatric patients.
  • Incorporates latest evidence for clinical decision-making.

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