Related Experiment Video
Updated: Jan 29, 2026

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure
Published on: February 12, 2018
Clinical evaluation of a transmission detector system and comparison with a homogeneous 3D phantom dosimeter
Francesca Romana Giglioli1, Elena Gallio1, Pierfrancesco Franco2
1Medical Physics Unit, A.O.U. Città della Salute e della Scienza, Corso Bramante 88/90, 10126 Turin, Italy.
Purpose:
To evaluate the performances of the Dolphin system for pre-treatment verification (IBA Dosimetry, Schwarzenbruck, Germany) based on transmission measurements, employing a clinical perspective.
Methods And Materials:
Fifty treatment plans were verified by Dolphin and Delta4 detectors (Scandidos, Uppsala, Sweden) during the same session and subsequently by the Delta4 itself. The attenuation factor of the transmission detector (required for on-line dosimetry) was evaluated by comparing Delta4 measurements with and without Dolphin. Gamma evaluation was performed to compare the plan dose with the one delivered in case of Delta4 and Dolphin (gamma analysis within the structures). Dose-volume based parameters for PTV and OARs doses were considered for Compass calculation and Dolphin reconstruction and clinical decisions were made by two expert physicians in order to assess the "pass", "fail" or "evaluate" grade of the treatment plans. A statistical analysis was performed to investigate the eventual correlation between Delta4 gamma analysis and Dolphin clinical evaluation.
Results:
A value of 10.7% ± 0.7% was found for detector attenuation. No patients were classified as "fail" by the two instruments as well as by physicians. No correlation was found between the Delta4gamma metric and physician classification; conversely, a significant correlation was observed for Dolphin between the numbers of points with gamma ≥1 (gamma failure rate, as evaluated by the Dolphin) in the PTV area and clinical decision.
Conclusion:
The Dolphin system demonstrated to be an accurate detector for pre-treatment purposes and could be used as a clinical decision making tool for plan acceptance.
Related Concept Videos
Test for Homogeneity
Gas Chromatography: Types of Detectors-I
TCD is the earliest and most widely used detector that operates by measuring the changes in the thermal conductivity of the carrier gas. When a sample compound enters the detector,...
The Sense of Self: Reflected Self-Appraisal and Social Comparison
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Gas Chromatography: Overview of Detectors
A non-destructive detector allows a sample to be analyzed without altering or consuming it, meaning the sample can be collected after detection for further analysis. Examples include thermal conductivity detectors and...

