Screening for hepatitis B virus and accelerated vaccination schedule in prison: A pilot multicenter study

Area of Science:

• Epidemiology
• Public Health
• Vaccinology

Background:

• Hepatitis B virus (HBV) infection poses a significant risk in correctional facilities.
• Effective HBV vaccination strategies are crucial for preventing infection transmission.
• Understanding HBV prevalence in prisons informs targeted public health interventions.

Purpose of the Study:

• To assess the epidemiological impact of HBV in Tuscany region prisons.
• To increase hepatitis B vaccination coverage among inmates using an accelerated schedule.

Main Methods:

• Serum screening for HBV markers was conducted on detainees in 15 of 17 Tuscany region facilities.
• An accelerated vaccination schedule was offered to susceptible inmates.
• Vaccination uptake and completion rates were recorded.

Main Results:

• Out of 1075 screened inmates, 730 (67.9%) were susceptible to HBV infection.
• 596 inmates (82% of susceptible) agreed to vaccination.
• High vaccination completion rates were observed: 95.1% received the first dose and 83% completed the third dose.

Conclusions:

• A substantial proportion of the prison population requires HBV vaccination.
• The accelerated vaccination schedule successfully achieved high vaccination coverage.
• This approach enhances HBV prevention in correctional settings.