Related Experiment Video
Updated: Jan 29, 2026

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD
Published on: October 10, 2012
The Extracellular Protein, Transthyretin Is an Oxidative Stress Biomarker
Meesha Sharma1, Sheeza Khan1, Safikur Rahman2
1Dr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, India.
Abstract:
The extracellular protein, transthyretin is responsible for the transport of thyroxin and retinol binding protein complex to the various parts of the body. In addition to this transport function, transthyretin has also been involved in cardiovascular malfunctions, polyneuropathy, psychological disorders, obesity and diabetes, etc. Recent developments have evidenced that transthyretin has been associated with many other biological functions that are directly or indirectly associated with the oxidative stress, the common hallmark for many human diseases. In this review, we have attempted to address that transthyretin is associated with oxidative stress and could be an important biomarker. Potential future perspectives have also been discussed.
Related Concept Videos
Oxidation Numbers
The Extracellular Matrix
Pyruvate Oxidation
First, the enzyme pyruvate dehydrogenase removes the carboxyl group from pyruvate and releases it as carbon dioxide. The stripped molecule is then oxidized and releases electrons, which are then picked up by NAD+...
Oxidation-Reduction Reactions
Responses to Heat and Cold Stress
Responses to Salt Stress

