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International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure
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Guiding Principles for the Recognition, Diagnosis, and Management of Infants with Anaphylaxis: An Expert Panel

Matthew Greenhawt1, Ruchi S Gupta2, J Allen Meadows3

  • 1Section of Allergy and Immunology, Food Challenge and Research Unit, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colo.

The Journal of Allergy and Clinical Immunology. in Practice
|February 10, 2019
PubMed

Insights

Infant anaphylaxis, often caused by food allergies, presents unique challenges in recognition and treatment for nonverbal infants. Expert guidance is developing to improve diagnosis and management of this emerging risk.

Area of Science:

  • Pediatric Allergy and Immunology
  • Emergency Medicine
  • Neonatal Care

Background:

  • Infant anaphylaxis is an increasing concern, primarily triggered by food allergies.
  • Recognizing anaphylaxis in infants is difficult due to overlapping symptoms with normal infant behaviors.
  • Optimal treatment and diagnosis face real-world challenges in nonverbal infants.

Framework:

  • Expert panel convened to establish guiding principles for infant anaphylaxis recognition, diagnosis, and management.
  • Developed a framework to guide future infant anaphylaxis guidelines and research initiatives.
  • Addressed emergency action planning specifically for infants experiencing anaphylaxis.

Implementation:

  • Intramuscular epinephrine remains the primary treatment for infant anaphylaxis.
  • FDA-approved epinephrine autoinjectors are now available for infants weighing 7.5-15 kg.
  • Healthcare providers need enhanced awareness for improved infant anaphylaxis care.

Implications:

  • Future research should focus on validating clinical criteria for infant anaphylaxis diagnosis.
  • Identifying risk factors for severe anaphylactic reactions in infants is crucial.
  • Improved recognition, diagnosis, and management strategies are needed for infant anaphylaxis.

Keywords:
AnaphylaxisEpinephrineEpinephrine autoinjectorFood allergyInfant anaphylaxisNeedle length

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