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Related Concept Videos

Inflammatory Response01:28

Inflammatory Response

16.6K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
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Inflammatory Response II: Inflammatory Exudate and Tissue Repair01:24

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

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The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
7.7K
Inflammatory Response I: Vascular and Cellular01:30

Inflammatory Response I: Vascular and Cellular

16.3K
The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
16.3K
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
978
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

514
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
514
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

1.0K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.0K

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Isolating Malignant and Non-Malignant B Cells from lck:eGFP Zebrafish
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Paraduodenal inflammatory pseudotumor masquerading as malignancy.

June S Peng1, Haiyan Lu2, Michael W Cruise2

  • 1Department of General Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

BMJ Case Reports
|February 10, 2019
PubMed
Summary

A patient with abdominal pain had two masses found. Surgical removal of a paraduodenal mass revealed an inflammatory pseudotumor, resolving her symptoms.

Keywords:
cancer interventiongastrointestinal surgerygeneral surgerypathologystomach and duodenum

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Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Abdominal pain and distension can indicate intra-abdominal masses.
  • Accurate diagnosis of abdominal masses is crucial for effective treatment.

Observation:

  • A 30-year-old woman presented with severe abdominal pain and distension.
  • CT imaging revealed two intra-abdominal masses: one in the liver and another near the duodenum.

Findings:

  • Initial biopsies suggested focal nodular hyperplasia of the liver and non-specific lymphocytic infiltrate in the paraduodenal mass.
  • Laparoscopic resection of the paraduodenal mass was performed due to persistent symptoms.
  • Final pathology confirmed the paraduodenal mass as an inflammatory pseudotumor.

Implications:

  • Inflammatory pseudotumors can mimic other abdominal pathologies.
  • Surgical resection can be curative for symptomatic inflammatory pseudotumors.
  • This case highlights the importance of definitive histopathological diagnosis for intra-abdominal masses.