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Prevalence and current therapy in chronic liver disorders
Muhammad Daniyal1, Muhammad Akram2, Rida Zainab3
1TCM and Ethnomedicine Innovation and Development International Laboratory, School of Pharmacy, Innovative Materia Medica Research Institute, Hunan University of Chinese Medicine, Changsha, 410208, People's Republic of China.
Traditional herbal medicines are widely used globally for liver diseases due to their efficacy and fewer side effects compared to conventional treatments. Further research is needed to integrate these hepatoprotective plant compounds into evidence-based therapies.
Area of Science:
- Pharmacognosy
- Hepatology
- Ethnobotany
Background:
- Herbal medicine is crucial in healthcare, especially in underserved regions, with WHO estimating 75% of the global population uses traditional remedies.
- Medicinal plants are increasingly explored for treating liver diseases like hepatitis and cirrhosis due to potential side effects of allopathic medicines.
Purpose of the Study:
- To review the scientific literature on the hepatoprotective effects of various medicinal plants.
- To identify chemical constituents in plants that exhibit liver-protective properties.
Main Methods:
- A comprehensive literature search was conducted across major scientific databases: PubMed, Medline, and Google Scholar.
- Studies focusing on the hepatoprotective properties of plants were included.
Main Results:
- Numerous medicinal plants are utilized worldwide for liver disorder treatment, often alongside conventional medicine.
- Hepatoprotective plants contain diverse bioactive compounds, including flavonoids, alkaloids, phenols, and essential oils.
Conclusions:
- The review confirms that many plants possess compounds with demonstrated hepatoprotective activity.
- Further research is essential to validate these findings, explore integration with antiviral therapies, and develop evidence-based herbal treatments for human liver diseases.
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