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Updated: Jan 29, 2026

Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis
Published on: August 12, 2019
L-Thyroxine induces thermotolerance in yeast
Konstantinos Papamichael1,2, Basil Delitheos3, Iordanis Mourouzis3
1Department of Pharmacology, Medical School, National and Kapodistrian University of Athens, M. Asias 75, GR-11527, Athens, Greece. kpapamdoc@yahoo.gr.
Abstract:
The cellular stress response (CSR) is a universal inducible reaction modulated, among others, by heat, drugs, and hormones. We aimed to investigate the role of L-thyroxine (T4) on the heat shock (HS) response in Saccharomyces cerevisiae. The CSR was evaluated by determining growth and viability of post-logarithmic phase grown yeast cultures after HS at 53 °C for 30 min. We found that long-term T4 exposure can induce a dose-dependent and Hsp90 and H+ trafficking-related thermotolerance in yeast.
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