Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Retinitis pigmentosa. Visual loss.

Archives of Ophthalmology (Chicago, Ill. : 1960)

|July 1, 1978

Summary

This summary is machine-generated.

Genetic type influences central visual loss in retinitis pigmentosa (RP). Autosomal-dominant RP showed mildest vision loss, while X-linked recessive RP had the most extensive central visual impairment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Clinical value, normative retinal sensitivity values, and intrasession repeatability using a combined spectral domain optical coherence tomography/scanning laser ophthalmoscope microperimeter.

Eye (London, England)·2010

Same author

Cystic macular oedema on spectral-domain optical coherence tomography in choroideremia patients without cystic changes on fundus examination.

Eye (London, England)·2010

Same author

Rod increment thresholds in cone-rod dystrophy.

Applied optics·2010

Same author

Properties of the human cone system electroretinogram during light adaptation.

Applied optics·2010

Same author

Selective thinning of the perifoveal inner retina as an early sign of hydroxychloroquine retinal toxicity.

Eye (London, England)·2010

Same author

Predicting the pathogenicity of RPE65 mutations.

Human mutation·2009

Same journal

The economics of the initial preventive physical examination in medicare-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

Modification of silicone oil retention sutures in aphakic eyes with iris loss-reply;.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

December 2011 archives web quiz winner.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

Angle involvement and glaucoma in patients with biopsy-proven iris melanoma: a response-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

About this journal.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

In memoriam: goodwin m. Breinin, MD (1918-2011).

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

See all related articles

Area of Science:

Ophthalmology
Genetics
Retinal Diseases

Background:

Retinitis pigmentosa (RP) is a group of inherited retinal diseases.
Understanding genetic subtypes is crucial for predicting disease progression and visual outcomes.
Central visual loss significantly impacts patient quality of life.

Purpose of the Study:

To investigate the relationship between genetic inheritance patterns and the degree of central visual loss in retinitis pigmentosa.
To provide data that can aid in patient counseling regarding visual prognosis.

Main Methods:

Categorization of 174 retinitis pigmentosa patients (347 eyes) based on genetic type.
Assessment of the degree of central visual loss for each genetic subtype.
Statistical analysis of visual acuity data.

Related Experiment Videos

Main Results:

Central visual loss was mildest in autosomal-dominant retinitis pigmentosa.
Central visual loss was most extensive in X-linked recessive retinitis pigmentosa.
34% of all eyes had visual acuity of 20/200 or less; 55% had vision of 20/60 or better.

Conclusions:

Genetic type is a significant factor in the severity of central visual loss in retinitis pigmentosa.
Findings offer guidelines for counseling patients on potential future visual impairment.
Further research into genotype-phenotype correlations in RP is warranted.